To review:
The outcome of a toxin that results in creating the same length of the refractory period in cardiac muscles as present in the skeletal muscles.
Introduction:
The heart muscles generate an action potential due to the depolarization of the sinoatrial node (SA node) of the heart, which acts as a natural pacemaker. The action potential leads to muscular contraction, which helps the heart to supply blood to the whole body. The other cells that have the capability to generate an action potential as a result of the depolarization are the skeletal muscle cells and the neuron cells. After one action potential is generated, the cell becomes resistant to generating another action potential for a few seconds. This period is termed as the refractory period.
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Human Anatomy & Physiology
- The role of the bundle of his, bundle branches, and purkinje fibers is to Help conduct the electrical pulse (action potential) to the top of the heart first before allowing the contraction to spread to the atria. Help conduct the electrical pulse (action potential) to the whole ventricle. Help conduct the electrical pulse (action potential) to the bottom of the heart first to allow it to spread from the bottom to the top of the heart. To allow the electrical pulse (action potential) to pause for 0.1s before spreading to the ventricle.arrow_forwardFill in the following blanks (a - f) regarding the Baroreceptor Reflex Control: The baroreceptor reflex control is a negative feedback loop. If the patient is hypotensive, they are experiencing a decrease in blood pressure detected by (a.)_ located in the aortic and carotid bodies. The afferent pathways include the (b.)_ nerve and the (c.)__ nerve. These synapse at the cardioregulatory and vasomotor integration centers located in the (d.)_ These centers will cause the heart rate to (e.)(increase/decrease) and blood vessels to (f.) (vasodilate/vasocontrict). For the toolbar press ALT+510 (BC) or ALTHEN±+510/Madarrow_forwardThe plasma membranes of adjacent cardiac muscle cells are connected via ____________, in which ____________ tie the cells together and ____________allow current (ions) to flow from one cell to the next (electrical coupling).arrow_forward
- Caffeine lowers the heart rate by increasing rates of depolarization at the SA node True False Nicotine raises the heart rate because it stimulates the activity of the sympathetic neurons in medulla oblongata True False The Frank-Starling Law of the Heart states that the force of heart contraction is directly proportional to the initial length of the muscle fiber, within optimal limits of length True False If the sarcomeres stretched beyond the optimal length, the force of contraction would go down, but that can potentially happen only during open heart surgery when the heart is not constrained by the pericardium, lungs, ribs and diaphragm. True False It is the Na+ channel-driven spontaneous depolarization that is affected by sympathetic and parasympathetic inputs to speed up or slow down the firing rate of the SA node and other conductive cells. True Falsearrow_forwardActivation of β2-adrenergic receptors in vascular smooth muscle stimulates vasodilation / vasoconstriction. Give an example of organs where this occurs.arrow_forwardWhy is pulse rate faster in small and young animals compared to that inlarge and older animals?arrow_forward
- Read this article (http://openstaxcollege.org/l/ strokespell) to learn about a teenager who experiences a series of spells that suggest a stroke. He undergoes endless tests and seeks input from multiple doctors. In the end, one expert, one question, and a simple blood pressure cuff answers the question. Why would the heart have to beat faster when the teenager changes his body position from lying down to sitting, and then to standing?arrow_forwardIn your study of neuron physiology, you learned that depolarization is dependent on the sodium entry (influx), and repolarization contingent on the potassium exit (efflux.) Compare the action potential in the heart’s intrinsic conduction and contractile cells, then explain why the electrocardiogram has different parts (P, QRS complex, and T wave.)?arrow_forwardCardiac muscle is described as being under involuntary control. Why is it that some individuals can seemingly “control” theirheart rate through meditation?arrow_forward
- You are supervising a student who is carrying out several experiments on an animal species that has cardiac muscle almost identical to that of humans. She has recorded the electrical and contractile response of the muscle after stimulation and asks you to take a look at the graph.arrow_forwardUnlike skeletal muscle, cardiac muscle doesn’t undergo tetany. Explain how this is achieved and why is this necessary?arrow_forwardExplain in detail why the neurotransmitter acetylcholine has different effects in skeletal vs. cardiac muscle cells.arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning