Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 17, Problem 2NST

The hormone estrogen converts the estrogen receptor (ER) protein from an inactive molecule to an active transcription factor. The activated ER binds to cis-acting sites that act as enhancers, located near the promoters of a number of genes. In some tissues, the presence of estrogen appears to activate transcription of ER-target genes, whereas in other tissues, it appears to repress transcription of those same genes. Offer an explanation as to how this may occur.

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Concepts of Genetics (12th Edition)

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