Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 17, Problem 2CS
The Joneses were referred to a clinical geneticist because their 6-month-old daughter was failing to grow adequately and was having recurrent infections. The geneticist took a detailed family history (which was uninformative) and a medical history of their daughter. He discovered that their daughter had a history of a constant cough and wheeze that was becoming progressively worse, had difficulty gaining weight (failure to thrive), and had an extensive history of yeast infection (thrush) in her mouth. The geneticist did a simple blood test to check their daughter’s white blood count and determined that she had severe combined immunodeficiency (SCID).
The geneticist explained that SCID is an immune deficiency that causes a marked susceptibility to infections. The defining characteristic is usually a severe defect in both the T- and B-lymphocyte systems. This results in one or more infections within the first few months of life that are serious and may even be life-threatening. Based on the family history, it was possible that their daughter had inherited a mutant allele from each of them and therefore was homozygous for a gene that causes SCID. If so, each time the Joneses had a child, there would be a 25% chance that the child would have SCID. Prenatal testing is available to determine whether the developing fetus has SCID.
If the Joneses want to be certain that their next child will not have SCID, what types of reproductive options do you think they have?
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The shape of radishes may be long (SL/SL), oval (SL/SS), or round (SS/SS), and the color of radishes may be red (CR/CR), purple (CR/CW) or white (CW/CW). If a long, red radish plant is crossed with a round, white plant, what will be the appearance of the F1 and F2 generations?
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Question #3:
In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would
transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming
there was just one gene conferring gametophytic obligate apomixis, and that the two parents are
inbreds, what would be the consequences of such a cross if:
a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non-
apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic
and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female
first (left side) in the parental cross.
b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non-
apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic
and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female
first (left side) in the…
Chapter 17 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 17.8 - One treatment for peanut allergies is to give an...Ch. 17.8 - Prob. 2EGCh. 17 - Prob. 1CSCh. 17 - The Joneses were referred to a clinical geneticist...Ch. 17 - The Inflammatory Response Is a General a. What...Ch. 17 - The Complement System Kills Microorganisms The...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 4QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 6QP
Ch. 17 - Prob. 7QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 9QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - It is often helpful to draw a complicated pathway...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 14QPCh. 17 - Prob. 15QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 17QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 19QPCh. 17 - Prob. 20QPCh. 17 - Prob. 21QPCh. 17 - Organ Transplants Must Be Immunologically A burn...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically A couple...Ch. 17 - Prob. 26QPCh. 17 - Disorders of the Immune System Antihistamines are...Ch. 17 - Disorders of the Immune System Autoimmune...Ch. 17 - Prob. 29QPCh. 17 - Prob. 30QPCh. 17 - Prob. 31QP
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