Concept explainers
a.
To determine: The ABO genotype of the three individuals.
Introduction: The blood group of an individual is determined by the presence of a certain kind of antigen on the surface of blood cells. A, B, AB, and O are four major blood groups found in human beings. The determination of the blood type of an individual is essential before the process of blood transfusion.
b.
To determine: The conclusions made by the court during the paternity suit.
Introduction: The blood group of an individual is determined by the presence of a certain kind of antigen on the surface of blood cells. A, B, AB, and O are four major blood groups found in human beings. The determination of the blood type of an individual is essential before the process of blood transfusion.
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Human Heredity: Principles and Issues (MindTap Course List)
- Number 10arrow_forwardTrue/falsearrow_forwardA 6-year-old girl with chronic anemia requiring repeated blood transfusions is undergoing genetic testing. The patient's mother and older sibling have a history of mild anemia. Her peripheral blood smear shows hypochromic, microcytic red blood cells, and sickle cells. Doctor has expressed opinion to use electrophoresis for diagnosis. Please explain how may it work for this disease?arrow_forward
- In the 1950s, A young woman sued film star/director Charlie Chaplin for parental support for her illegitimate child. Charlie Chaplin‘s blood type was already on record as type AB. The mother of the child had type B and her son had type O blood. The judge ruled in favor of the mother in order Charlie Chaplin to pay child-support cost for the child. Briefly explain why the judge was not correct in his decision based on blood typing evidence? arrow_forwardI understand that microarrays are being used to define the molecular abnormality and the prognosis in some patients with leukaemia. What are microarrays?arrow_forwardits itslearning /pdf-reader?job3D1617581334468 ... Tools ▼ A young woman in Hollywood sued a famous movie actor for support of her child, claiming that he was the father of her child. By typing the blood of the three persons involved, the following results were obtained: The child is type B; the Mother is type A; the Actor is type O. Could the actor have been the father? Explain. 5.arrow_forward
- XL 10 Gold cells and Express I^q cells. Give three differences between their genotypes and how each corresponds to their specific use in the labarrow_forwarddominant-therefore someone with AB genotype has AB phenotype. You can see both because they are codominant) i) What are the possible genotypes for someone with A blood type? ii) What about B blood type? iii) Let's assume that an person by the name of Dustin Beilber (this name sounds really familiar for some reason) is taken to trial in a paternity suit by a woman claiming that he is the father of her child. He claims he is not the father. At the trial, an expert witness reveals the blood types of all three: Dustin's blood type – B Mother's blood type – A Child's blood type – O Based on these data, is it possible that Dustin is the father of this child? (To put this in terms of the scientific method, you are trying to disprove the hypothesis that Dustin is the father). If you can't disprove this, it doesn't mean that he is the father, it simply means that you cannot reject the hypothesis). Explain your answer.arrow_forwardPlease helparrow_forward
- Several genes in humans in addition to the ABO gene () give rise to recognizable antigens on the surface of the red blood cells. The Rh marker is determined by positive (R) and negative alleles () of gene R, where R is completely dominant to r. The presence of M and N surface proteins are controlled by two codominant alleles of gene L (LM and LM. For each mother-child pair, choose the father of the child from among the males in the right column. (Assume that all mothers and fathers are HH; there is no involvement of the Bombay phenotype.) Paternal genotypes maybe used once, more than once, or not at all. Each mother-child pair matches with one or more than one paternal genotype. Maternal phenotype: Child phenotype: Paternal genotype: Reset A, M, Rh(neg) O, M, Rh(pos) B, N, Rh(neg) O, N, Rh(pos) O, M, Rh(neg) A, MN, Rh(pos) A, N, Rh(pos) AB, MN, Rh(pos) B, N, Rh(pos) A, MN, Rh(neg) Genotypes of possible fathers AiLMLN rr BiLMLN RR ii LNLN rr ii LMLM rr AALMLN RRarrow_forwardPlease help me understand. Thank you!arrow_forwardABO FORWARD TYPING Explain why absence of agglutination in A and B does not fully conclude type O phenotype. What is being detected in ABO Forward Typing? Why? Arrange the phenotypes of ABO Blood Group System from the most abundant of H antigen to the least abundant. Write the different sugars and enzymes involved in the synthesis of type A, B, AB, and O phenotypes. ABO REVERSE TYPING What is the recommended blood typing method for neonates? Why? If the results for forward and reverse typing do not match, how will you proceed? What are the sources of error reverse typing?arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning