Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 17, Problem 19QP
a.
Summary Introduction
To determine: The genotypes of the parent when all their children have Rh+ blood group.
Introduction: There are two types of Rh blood groups: Rh+ (have Rh antigen) and Rh- (do not have Rh antigen). Rh factor is a point of concern when the mother has Rh- and fetus has Rh+ blood group. This condition can cause hemolytic disease of newborn baby (HDN).
b.
Summary Introduction
To determine: Whether the parents in the given case should be concerned about the risk of the occurrence of hemolytic disease to the newborn.
Introduction: There are two types of Rh blood groups: Rh+ (have Rh antigen) and Rh- (do not have Rh antigen). Rh factor is a point of concern when the mother has Rh- and fetus has Rh+ blood group. This condition can cause hemolytic disease of newborn baby (HDN).
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Below are the ABO and Rh blood types of some couples. If during birth some blood is exchaged between the mother and the first newborn, the second newborn of which couple has the LEAST chance for suffering from hemolytic disease of the newborn due to Rh incompatibility? Consider both Rh and ABO incompatibilities.
A.
Wife B -, husband O +
B.
Wife AB -, husband AB +
C.
Wife AB -, husband O+
D.
Wife O -, husband B +
E.
Wife A -, husband O+
Give the Blood Type of the Following Genotypes (Review Rh genetics in the ABO Lab Document and Bombay Phenotype)
Genotype Phenotype (Blood type)
a) IAIB CcDDeeHh ___ (+ or -)
b) IAi CcddEehh ___
c) ii ccddeehh ___
d) IBIB Ccddeehh ___
A child with the "B positive” blood type is known to be a heterozygote at both the ABO blood type gene and also the Rh blood type gene. What is the genotype of this child at these two genes?
Chapter 17 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 17.8 - One treatment for peanut allergies is to give an...Ch. 17.8 - Prob. 2EGCh. 17 - Prob. 1CSCh. 17 - The Joneses were referred to a clinical geneticist...Ch. 17 - The Inflammatory Response Is a General a. What...Ch. 17 - The Complement System Kills Microorganisms The...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 4QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 6QP
Ch. 17 - Prob. 7QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 9QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - It is often helpful to draw a complicated pathway...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 14QPCh. 17 - Prob. 15QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 17QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 19QPCh. 17 - Prob. 20QPCh. 17 - Prob. 21QPCh. 17 - Organ Transplants Must Be Immunologically A burn...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically A couple...Ch. 17 - Prob. 26QPCh. 17 - Disorders of the Immune System Antihistamines are...Ch. 17 - Disorders of the Immune System Autoimmune...Ch. 17 - Prob. 29QPCh. 17 - Prob. 30QPCh. 17 - Prob. 31QP
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- Briefly explain the ABO blood groupings. Include how they are determined and what they actually are, and what happens when two types are not compatible. Then, complete the table below by indicating all blood types that are compatible (ignoring all other blood groupings such as Rh). If you have blood type A B AB O Then you can get a transfusion of blood typearrow_forwardIn blood groups, Rh positive blood is dominant (R) over the gene for Rh negative blood (r). What types of offspring could be expected for an Rh positive AB woman, (whose father was Rh negative), who marries a man with heterozygous A positive blood?arrow_forwardWhat would the offspring's blood type be if the mother is type O+ (she is homozygous for Rh factor) and the father is A- (he is homozygous for type A)? Hint: You have to do two Punnett squares. The two Punnett squares must be shown to get the full points. After doing the Punnett squares, write down the possibilities of the offspring’s blood type.arrow_forward
- A mom that is AB+ had a son with a B- man. Describe all possible gametes both parents could produce and list all possible blood types the baby could have, what antigens these blood types would have and what antibodies would be produced in the individual with these blood types. Lastly, explain why this baby would have a hemolytic diseasearrow_forwardThere is a lesser-known phenomenon of maternal fetal ABO incompatibility. Why is this much less common than Rh incompatibility? (Hint: think about the Ig classes involved in each)arrow_forwardA phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac?arrow_forward
- Draw punnett square of the following: 50% of their children will be female carriers and 25% of their children will have DMD.arrow_forwardGiven: Father - heterozygous for the H locus of the H antigen, heterozygous for the B locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and deuteranope Mother - heterozygous for the H locus of the H antigen, heterozygous for the A locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and carrier for the trait deuteranopia Task: Using the line fork method, determine the probabilities in ratio form of all possible phenotype combinations of the traits in the biological offspring of the couple. Include the solutionarrow_forwardAn A+ male impregnates a woman who is unsure of her blood type. Which blood type would the mother have to be for the baby to be at risk of a hemolytic disease?arrow_forward
- Rh factors are proteins that were first discovered in the blood of Rhesus Monkeys, but humans have them too. If you are Rh positive, it means that there are Rh type proteins in your blood. If you are Rh negative, there are no Rh type proteins in your blood. Positive is dominant over negative, so heterozygous individuals are Rh positive. Problems can arise when an Rh negative mother has a child who is Rh positive. Which of the statements will answer the following questions: Why does the mother's body attack her own baby in this situation? Why does the situation get worse for the second pregnancy? a. The mother's body sees the foreign proteins produced by her baby as a threat. She builds up antibodies against them. b. Her immune system attacks the baby, often resulting in a miscarriage. Immune suppressing drugs can be given to the mom, but then she's more likely to get sick because her body's germ fighting ability is diminished. c. The baby is delivered before the situation gets too…arrow_forwardA graduating nursing student wanted to know the different blood groups and how they can be inherited. She understood that multiple allele is the inheritance pattern for ABO blood type while complete dominance for Rh factor (Rh + is dominant over Rh -). Now she wanted to know what the probable blood types from the 3 systems on her future children are. Consider the nursing student has AB, Rh negative and her current husband has O, heterozygous Rh positive. 1. What is the probability of having a child with a blood type of type O? A. 25% B. 100% C. 75% D. 50% E. 0% 2. What is the probability of having a child with a blood type of type A Rh positive? A. 1/4 B. 3/8 C. 1/2 D. 3/4 E. 1/8 3. What is the probability of having a child with a blood type of type B Rh negative? A. 3/4 B. 1/8 C. 1/4 D. 1/2 E. 3/8 4. heterozygous Rh positive. What are the possible blood types of her children? A. A Rh+, A Rh-, B Rh+, B Rh-, O Rh+, O Rh- B. A Rh+, B…arrow_forwardA woman whose blood type is A- is planning on starting a family with a B+ blood type man. Which of the following is the most accurate advice that you could give to this couple based on their blood types? They should be concerned about hemolytic disease of the newborn for all of their pregnancies . Since the woman is Rh-, she produces anti-Rh antibodies. Since the man is Rh+, the fetus in all pregnancies with this man will also be Rh+. This means that the mom?s anti-Rh antibodies will destroy fetal RBCs every time that the woman gets pregnant, thus producing a dangerous anemia to all the fetuses from all pregnancies with this man. They should be concerned about hemolytic disease of the newborn. However, problems related to this condition seldom develop during a first pregnancy, because very few fetal cells enter the maternal bloodstream then, and thus the mother?s immune system is not stimulated to produce anti-Rh antibodies. However if a future pregnancy with the…arrow_forward
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