Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 17, Problem 30QP
Summary Introduction

To identify: The step of antibody-mediated immune response pathway in which the AIDS patient are deficient.

Introduction: AIDS stands for acquired immunodeficiency syndrome. This is caused by the human immune deficiency virus (HIV). The patients infected with HIV suffer from a collection of disorders. Worldwide about 33 million people are infected with HIV.

Summary Introduction

To determine: The reason why the human body cannot fight off HIV infection.

Introduction: The antibody-mediated immune response protects the body against viruses and bacteria. The antibody-mediated immune response uses antibodies produced by plasma cells to specifically attack and destroy antigens. T-helper cells play an important role in the activation of B-cells.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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Human Heredity: Principles and Issues (MindTap Course List)

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