(a) Interpretation: The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity. Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Question

Want to see the full answer?

Answer 1

Question

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!

Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)

Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?

Answer 2

Question

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Answer 6

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Answer 7

Chapter 17, Problem 13P

Interpretation Introduction

(a)

Interpretation:

The way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Answer 8

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Answer 9

Interpretation Introduction

(a)

Interpretation:

If patients respond to DCA, then conclude the activity of pyruvate dehydrogenase.

Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It converts the pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 13

Ch. 17 - Prob. 1P Ch. 17 - Prob. 2P Ch. 17 - Prob. 3P Ch. 17 - Prob. 4P Ch. 17 - Prob. 5P Ch. 17 - Prob. 6P Ch. 17 - Prob. 7P Ch. 17 - Prob. 8P Ch. 17 - Prob. 9P Ch. 17 - Prob. 10P

Solution Summary: The author explains the way in which dichloroacetate or DCA stimulates the pyruvate dehydrogenase activity.

Concept explainers

Videos

Want to see the full answer?

Chapter 17 Solutions