The reason malonic acid act as a competitive inhibitor and not a substrate for succinate dehydrogenase should be determined. Effect on the concentration of intermediates of the cycle, after the addition of malonic acid to citric acid cycle, should be determined. Concept introduction: The citric acid cycle is a catabolic process. It is a series of chemical reactions in which the stored energy of the body is released by the oxidation of acetyl-Coenzyme A. Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Question

Want to see the full answer?

Answer 1

Question

Chapter 17, Problem 24P

Interpretation Introduction

Interpretation:

The reason malonic acid act as a competitive inhibitor and not a substrate for succinate dehydrogenase should be determined.

Effect on the concentration of intermediates of the cycle, after the addition of malonic acid to citric acid cycle, should be determined.

Concept introduction:

The citric acid cycle is a catabolic process. It is a series of chemical reactions in which the stored energy of the body is released by the oxidation of acetyl-Coenzyme A. Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

2. For the flow of fluid over a flat membrane of length 10cm, determine the length-average mass transfer coefficient. The relevant properties of the system are u=0.01cm²/s, D=5 x 106 cm²/s, and v = 5.0 cm/s.

Background Freezing isn't the only challenge in cryopreservation - thawing can be just as difficult. A microwave oven seems like a nice solution, since it deposits energy quickly and microwaves are non-ionizing radiation (they do not cause DNA mutation). However, water absorbs microwaves more effectively than ice does, meaning that the portion of an organ that has already melted will get warmer at a higher rate than the remaining ice – the opposite of what we want! - The transmission of radiation through a weakly absorbing material such as ice or water can be modeled by Beer's law, which assumes that the rate of absorption at a depth x is proportional to the local radiation intensity I(x) times an absorption coefficient, which is often written as μ or a or just µ). Noting that absorption decreases the intensity, we can write a differential equation a Solving the differential equation with the boundary condition on the surface being gives the relationship For a standard microwave oven…

3. Dry air is inhaled at a rate of 10 liter/min through a trachea with a diameter of 20 mm and a length of 125 mm. The inner surface of the trachea is at a normal body temperature of 37°C and may be assumed to be saturated with water. a. Assuming steady, fully developed flow in the trachea, estimate the mass transfer convection coefficient. b. Estimate the daily water loss (liter/day) associated with evaporation in the trachea.