Biochemistry
Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 17, Problem 36P
Interpretation Introduction

(a)

Interpretation:

The amount of O2 absorbed by complete oxidation of added citrate is to be calculated.

Concept introduction:

The activity of the citric acid cycle can be observed by accounting the amount of O2. H. Krebs conducts the experiment on pigeon-breast muscle to investigate that the rate of citric acid cycle grows with the increased rate of O2 consumption.

The citric acid cycle is the third step of the biochemical energy production process. The cycle consists of the reactions from which the acetyl part of acetyl CoA is oxidized to form carbon dioxide and CoA-SH.

Interpretation Introduction

(b)

Interpretation:

On the basis of the result in part (a), consumption of oxygen in the presence of citrate is to be explained.

Concept introduction:

The activity of citric acid cycle can be observed by accounting the amount of O2. H. Krebs conducts the experiment on pigeon-breast muscle to investigate that rate of citric acid cycle increases with the increased rate of O2 consumption.

The balanced reaction of complete oxidation of citrate is,

C6H8O7+4.5O26CO2+4H2O

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