Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15.1, Problem 4COMQ
Regulatory transcription factors can be modulated by
a. the binding of small effector molecules.
b. protein-protein interactions.
c. covalent modifications.
d. all of the above.
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Students have asked these similar questions
Which of the following is true of CpG islands?
a. They are methylated near promoters of actively transcribed genes.
b. They are unmethylated near promoters of actively transcribed genes.
c. Acetylation of CpG islands leads to repression of transcription.
d. CpG islands code for RNA molecules that activate transcription.
State true or false, giving a brief justification:
a. An enhancer is a type of regulatory element.
b. A core promoter is a type of regulatory element.
c. Regulatory transcription factors bind to regulatory elements.
d. Typically, an enhancer may
cause the downregulation of transcription.
Enhancers:
a.
are always located upstream of the TATA sequence
b.
are always within 200 bp of the TATA sequence
c.
are responsible for time and tissue specific transcription
d.
All the above are true.
Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Is each of the following statements true or false? A. An enhancer is a type of regulatory element. B. A core promoter is a type of regulatory element. C. Regulatory transcription factors bind to regulatory elements. D. An enhancer may cause the down regulation of transcription.arrow_forwardCombinatorial control refers to the phenomenon that a. transcription factors always combine with each other when regulating genes. b. the combination of many factors determines the expression of any given gene. c. small effector molecules and regulatory transcription factors are found in many different combinations. d. genes and regulatory transcription factors must combine with each other during gene regulation.arrow_forwardAll genes regulated by PKA contain a cis-acting DNA sequence that binds to the phosphorylated form of a transcription factor called (choose one answer) a. CREB. b. C-Jun. c. beta-catenin. d. TCF.arrow_forward
- Alternative RNA splicing a. is a mechanism for increasing the rate of transcription. b. can allow the production of proteins of different sizes from a gene. C. can allow the production of similar proteins from different RNAS. d. increases the rate of transcription. e. is due to the presence or absence of particular snRNAs.arrow_forward. Which of the following is an example of post-transcriptional gene repression?a. The amount of RNA transcribed from a gene isreduced because the DNA is methylated.b. The amount of RNA is reduced because it is rapidlydegraded.c. The amount of protein made is reduced by action ofan miRNA.d. b and c are both correct.arrow_forwardA transcription factor (protein - orange/green) is bound to a promoter of a gene (DNA - blue) it regulates. What changes would result in the gene not being expressed? A. Mutations in the DNA sequence where the TF is bound B. Mutations in the DNA binding domain of the TF C. Mutations in the 3’UTR (untranslated region) of this gene A and B only B and C only A, B, and Carrow_forward
- How does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choicearrow_forwardGene expression regulation by methylation of the cytosines in a promoter would be considered : Select one: a. Translational regulation. b. Transcriptional regulation. c. Posttranscriptional regulation. d. Posttranslational regulation.arrow_forwardDistant regulatory sites are called: a. Enhancers b. Operators c. Both a and b d. None of the abovearrow_forward
- Which of these is used in the transcription of all genes? Choose all correct answers. A. Core promoter B. Proximal promoter C. Distal promoter D. General Transcription Factors E. Regulatory Transcription Factorsarrow_forwardFor each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosomearrow_forwardWhich of the following will lead to a decrease in transcription of a gene? A. Increase in histone acetyltransferases. B. Decrease in CpG methylation of promoter. C. Increase in histone deacetylases. D. Decrease in DNA methyltransferases.arrow_forward
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