Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 15, Problem 7P
What are the roles of the Polycomb and Trithorax complexes in eukaryotic gene regulation?
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Why is transcription a particularly important level of gene regulation in both bacteria and eukaryotes?
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Chapter 15 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 15 - 13.1 Devoting a few sentences to each, describes...Ch. 15 - 13.2 Describe and give an example (real or...Ch. 15 - What is meant by the term chromatin remodeling?...Ch. 15 - 13.4 What general role does acetylation of histone...Ch. 15 - 13.5 Describe the roles of writers, readers, and...Ch. 15 - Outline the roles of RNA in eukaryotic gene...Ch. 15 - 13.7 What are the roles of the Polycomb and...Ch. 15 - Most biologists argue that the regulation of gene...Ch. 15 - Compare and contrast the transcriptional...Ch. 15 - The term heterochromatin refers to heavily...
Ch. 15 - 13.11 Compare and contrast promoters and enhancers...Ch. 15 - 13.12 What are the different chromatin...Ch. 15 - 13.13 Define epigenetics, and provide examples...Ch. 15 - What is one proposed role for lncRNAs?Ch. 15 - 13.17 A hereditary disease is inherited as an...Ch. 15 - Prob. 16PCh. 15 - A gene expressed in long muscle of the mouse is...Ch. 15 - The consequences of four deletions from the region...Ch. 15 - Provide a description of the mechanistic roles of...Ch. 15 - 13.20 A muscle enzyme called ME is produced by...Ch. 15 - 21. A muscle protein in mouse is produced through...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the functions of transcriptional activator proteins and repressor proteins? Explain how they work at the molecular level.arrow_forwardSelect the following descriptions of gene transcription regulation in eukaryotes that are post-translational: Select 2 correct answer(s) O A) Length of poly A tail B) Chromatin modification C) Destruction of protein before/after modifications by a proteosome U D) Alternative splicing of mRNA molecule E) Acetylation of histone tails F) Binding of activators to enhancers regions on the DNA G) destruction of mRNA by RNA interference O H) DNA methylation UI) Addition of functional groups to a fully formed proteinarrow_forwardWhat are the two important sequence elements in the prokaryotic gene promoter? How does the RNA polymerase find the promoter?arrow_forward
- Why is it said that transcriptional regulation in eukaryotes is characterized by combinatorial interactions?arrow_forwardWhat are three mechanisms by which transcription factors regulate eukaryotic gene expression?arrow_forwardHow do nucleosomes add to the complexity of eukaryotic transcription?arrow_forward
- For each of the following, identify whether that sequence or feature of a typical protein-coding gene would be recognizable in the specified molecule in a typical prokaryotic cell. 5' UTR in DNA? 5' UTR in mRNA? Shine-Dalgarno in DNA? Shine-Dalgarno in polypeptide? Promoter in RNA? Promoter in polypeptide sequence? Stop codon in mRNA? Stop codon in the polypeptide sequence? [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] > <arrow_forwardWhat is the fundamental difference in how bacterial andeukaryotic genes are regulated?arrow_forwardWhat are some approaches to gene regulation in eukaryotes discussed in class(epigenetic, enhances, RNA splicing)?arrow_forward
- The Dscam locus in Drosophila melanogaster has 24 exons. Four of these exons are able to undergo alternative splicing. Exon 4 has 12 possible splice variants, exon 6 has 48 variants, exon 9 has 33 variants, and exon 17 has 2 variants. If all splicing combinations are possible, how many different Dscam protein sequences could be encoded by a single allele at this locus?arrow_forwardSelect the following descriptions of gene transcription regulation in eukaryotes that are post-transcriptional/pre-translational: Select 3 correct answer(s) A) Acetylation of histone tails B) Length of poly A tail C) Alternative splicing of mRNA molecule D) Binding of activators to enhancers regions on the DNA E) Addition of functional groups to a fully formed protein F) DNA methylation G) Chromatin modification H) Destruction of protein before/after modifications by a proteosome I) destruction of mRNA by RNA interferencearrow_forwardThe locations of the TATA box in two species of yeast, Saccharomyces pombe and Saccharomyces cerevisiae, differ dramatically. The TATA box of S. pombe is about 30 nucleotides upstream of the transcription start site, similar to the location in most other eukaryotic cells. However, the TATA box of S. cerevisiae is 40 to 120 nucleotides upstream of the start site. To better understand what sets the start site in these organisms, researchers at Stanford University conducted a series of experiments to determine which components of the transcription apparatus of these two species could be interchanged (Y. Li et al. 1994. Science 263:805–807). In these experiments, different general transcription factors and RNA polymerases were switched in S. pombe and S. cerevisiae, and the effects of each switch on the level of RNA synthesis and on the starting point of transcription were observed. The results from one set of experiments are shown in the table below. Components cTFIIB, cTFIIE, cTFIIF,…arrow_forward
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