Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 15, Problem 4P
What general role does acetylation of histone proteinamino acids play in the transcription of eukaryoticgenes?
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How histone deacetylases (HDACs) remove acetyl groups from histone tails ?
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Chapter 15 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 15 - 13.1 Devoting a few sentences to each, describes...Ch. 15 - 13.2 Describe and give an example (real or...Ch. 15 - What is meant by the term chromatin remodeling?...Ch. 15 - 13.4 What general role does acetylation of histone...Ch. 15 - 13.5 Describe the roles of writers, readers, and...Ch. 15 - Outline the roles of RNA in eukaryotic gene...Ch. 15 - 13.7 What are the roles of the Polycomb and...Ch. 15 - Most biologists argue that the regulation of gene...Ch. 15 - Compare and contrast the transcriptional...Ch. 15 - The term heterochromatin refers to heavily...
Ch. 15 - 13.11 Compare and contrast promoters and enhancers...Ch. 15 - 13.12 What are the different chromatin...Ch. 15 - 13.13 Define epigenetics, and provide examples...Ch. 15 - What is one proposed role for lncRNAs?Ch. 15 - 13.17 A hereditary disease is inherited as an...Ch. 15 - Prob. 16PCh. 15 - A gene expressed in long muscle of the mouse is...Ch. 15 - The consequences of four deletions from the region...Ch. 15 - Provide a description of the mechanistic roles of...Ch. 15 - 13.20 A muscle enzyme called ME is produced by...Ch. 15 - 21. A muscle protein in mouse is produced through...
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- What is the process of inactivating the function of specificgenes in Eukaryotes ?arrow_forwardWhat are the functions of transcriptional activator proteins and repressor proteins? Explain how they work at the molecular level.arrow_forwardHow would a null mutation in the guanylyl transferase gene affect overall mRNA stability in eukaryotic cells?arrow_forward
- What does histone acetylation favor?arrow_forwardDescribe events associated with the process of transcription in eukaryotic cells. How is the process different in prokaryotic cells?arrow_forwardIn eukaryotes many transcriptional activators are dimers of related proteins. Assuming each dimer binds to one unique sequence, how many unique sequences can protein dimers derived from a family of six related proteins bind to?arrow_forward
- Why is it said that transcriptional regulation in eukaryotes is characterized by combinatorial interactions?arrow_forwardin a eukaryote cell, what do we call the DNA sequence that the specific transcription factor binds toarrow_forwardA drug called garcinol, isolated from Garcinia indica (a fruitbearing tree commonly known as kokum), is a potent inhibitor of histone acetyltransferase. Would you expect this drug to enhance or inhibit transcriptional initiation and elongation?arrow_forward
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