The blood test for syphilis was reactive in a 20-year-old college student. The student was indicated as a virgin and had never received any blood transfusion. The result of the repeat RPR diagnostic test was positive, however, the result of the TPI test was negative. Explain the contradictory results. Introduction: Syphilis is caused by Treponema pallidum. The major symptoms of syphilis are small lesion at the initial stage, skin and mucous membrane rashes, sore at the infected site, gummas, mild fever, malaise, loss of hair, cardiovascular, and nerve damage. It can be diagnosed by various serological tests, such as venereal disease research laboratory (VDRL) test, rapid plasma reagin (RPR) test, and fluorescent treponemalantibody-absorption (FTA-ABS) test. Benzathine penicillin is used to treat syphilis.

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Chapter 15, Problem 72E.2RQ

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To define: The blood test for syphilis was reactive in a 20-year-old college student. The student was indicated as a virgin and had never received any blood transfusion. The result of the repeat RPR diagnostic test was positive, however, the result of the TPI test was negative. Explain the contradictory results.

Introduction: Syphilis is caused by Treponema pallidum. The major symptoms of syphilis are small lesion at the initial stage, skin and mucous membrane rashes, sore at the infected site, gummas, mild fever, malaise, loss of hair, cardiovascular, and nerve damage. It can be diagnosed by various serological tests, such as venereal disease research laboratory (VDRL) test, rapid plasma reagin (RPR) test, and fluorescent treponemalantibody-absorption (FTA-ABS) test. Benzathine penicillin is used to treat syphilis.

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