MICROBIOLOGY F/HEALTH SCIENCES
18th Edition
ISBN: 9781323737798
Author: CAPPUCCINO
Publisher: PEARSON
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Chapter 15, Problem 71E.1RQ
Summary Introduction
To define: Why ELISA test is used to screen human serum for the AIDS virus, while Western blot techniques are used only as a confirmation test.
Introduction: Acquired immunodeficiency syndrome (AIDS) is a disease of the immune system caused by the human immunodeficiency virus (HIV). Human immunodeficiency virus is a sexually transmitted infection, and it can be spread from mother to child during breastfeeding, childbirth, infected blood transfusion, and sexual intercourse.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 15 Solutions
MICROBIOLOGY F/HEALTH SCIENCES
Ch. 15 - Prob. 1QCCh. 15 - Which serological test would the Infectious...Ch. 15 - How do precipitin and agglutination reactions...Ch. 15 -
How would you determine the optimal...Ch. 15 - Why is it essential to use a series of antigen...Ch. 15 - Prob. 69E.4RQCh. 15 - What are febrile antibodies?
What is their...Ch. 15 - What is the purpose of determining an antibody...Ch. 15 - Why does the antibody titer determination use...Ch. 15 - Why is the ELISA test used to screen human serum...
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