Concept explainers
(a)
Interpretation:
The chiral center of the clopidogrel needs to be labeled.
Concept introduction:
The molecules with a chiral center can form a superimposable mirror image and are known as enantiomers. There should not be any plane of symmetry in a molecule to be chiral. A plane that bisects a molecule into two equal halves is known as a plane of symmetry. If there is a plane of symmetry in a molecule and it is identical to any of its mirror image, it is considered as achiral. The chiral center is carbon attached to 4 different groups attached to it.
(b)
Interpretation:
The enantiomers of clopidogrel needs to be drawn.
Concept introduction:
The chiral molecules which are mirror images of each other are known as enantiomers. They are non-superimposable mirror images, or they cannot be placed on top of each other.
(c)
Interpretation:
The Fischer projections forClopidogrel needs to be drawn.
Concept introduction:
For a molecule with a chiral center, the Fischer projection formula is written to describe the stereo arrangement of atoms in two dimensions. For large molecules with more than 1 stereocenters are also represent their stereochemistry using the Fischer Projection. The carbon chain of the molecule containing the chiral carbon center is represented as a vertical line with chiral carbon at the center. Two other groups are then horizontally arranged around the chiral carbon atom.
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