Chapter 14, Problem 4P

Interpretation Introduction

Interpretation:

To determine the P/O ratio for oxidation of of $\alpha$ ketoglutarate, would malonate be included in your reaction system. Under such conditions what will be the P/O ratio.

Concept introduction:

The P/O ratio or the Phosphate to Oxygen ratio indicates the amount of ATP production by the movement of two electrons by the defined process of electron transport chain and are donated by the reduction of an oxygen atom. The P/O ratio has its dependence on the quantity of hydrogen atoms which are transported outward due to an electrochemical gradient and number of protons returning inward by the action of enzyme like ATP synthase.