Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Textbook Question
Chapter 14, Problem 10P
Years ago there was interest in using uncouplers such as dinitrophenol as weight control agents. Presumably, fat could be oxidized without concomitant ATP synthesis for re-formation of fat or carbohydrate. Why was this a bad (i.e., fatal) idea?
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Solution
? Hint
Sub
bo Each pictured Lewis structure is invalid. Identify the error in each case.
O Macmillan Learning
:0▬▬0:
Answer Bank
wrong electron total
:0-
:F======F:
octet-rule violation
N
:0:
[s] mM
V (M/s)
Uninhibited
0.333
1.65 x 107
1.05 x 107
V (M/s) x 10'
Inhibitor A
V (M/s) x 107
Inhibitor B
0.794 x 107
0.40
1.86 x 107
1.21 x 107
0.893 x 107
0.50
2.13 x 107
1.43 x 107
1.02 x 107
0.666
2.49 x 107
1.74 x 107
1.19 x 107
1.0
2.99 x 107
2.22 x 107
1.43 x 107
2.0
3.72 x 107
3.08 x 107
1.79 x 107
For a Michaelis-Menten reaction, k₁-5 x 10'/M-s, k.-2 x 10%/s, and k₂-4 x 10²/s.
a)
Calculate the Ks and KM for this reaction.
b)
Does substrate binding achieve equilibrium or steady state?
Chapter 14 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 14 - Prob. 1PCh. 14 - When pure reduced cytochrome c is added to...Ch. 14 - Freshly prepared mitochondria were incubated with...Ch. 14 - Prob. 4PCh. 14 - Prob. 5PCh. 14 - Prob. 6PCh. 14 - Intramitochondrial ATP concentrations are about 5...Ch. 14 - Prob. 8PCh. 14 - Prob. 9PCh. 14 - Years ago there was interest in using uncouplers...
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