The product formed in the given reaction has to be identified. Concept Introduction: Reaction of an ester having an α − hydrogen with one equivalent of a base to yield a β − keto ester. Mechanism for Claisen Condensation: A base abstracts a proton from the α − c a r b o n forms enolate ion. The enolate ion gets attached to the carbonyl carbon of another ester. The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Question

Want to see the full answer?

Answer 1

Question

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

22

PLEASE READ!!! I DONT WANT EXAMPLES, I DONT WANT WORDS OR PARAGRAPHS FOR THE MECHANISM!!! THANKS First image: QUESTION 6. I have to show, with ARROWS and STRUCTURES, the mechanism of the reaction at the bottom. Also I have to show by mecanism why the reaction wouldn't work if the alcohol was primary. I also tried to draw the mechanism, tell me what to change. Please note that its an AMIDE thats formed not an AMINE the nitrogen has ONE hydrogen and one Phenyl-C-Phenyl. I already asked for this mechanism and got as a final product ...-NH2 not whats shown on the picture, thank you Ths second part. QUESTION 3. I just need a way to synthesize the lactone A, I already started please continue from where I left it Second image: I simply need the products, substrates or reagents, thank you

Indicate how to prepare a 10% sodium hydroxide (NaOH) solution to a slightly alkaline pH.

Answer 2

Question

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Answer 6

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Answer 7

Chapter 13.8, Problem 17P

(a)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The product formed in the given reaction has to be identified.

Concept Introduction:

Reaction of an ester having an α− hydrogen with one equivalent of a base to yield a β− keto ester.

Mechanism for Claisen Condensation:

A base abstracts a proton from the α−carbon forms enolate ion.

The enolate ion gets attached to the carbonyl carbon of another ester.

The negative charge on oxygen of the carbonyl group reforms, by removing an alkoxide ion.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 13

Ch. 13.1 - Identify the most acidic hydrogen in each...Ch. 13.1 - Prob. 2P Ch. 13.1 - Prob. 3P Ch. 13.1 - Prob. 4P Ch. 13.1 - Explain why HO cannot remove a proton from the...Ch. 13.2 - Prob. 6P Ch. 13.2 - Prob. 7P Ch. 13.3 - Prob. 8P Ch. 13.3 - Prob. 9P Ch. 13.3 - Prob. 10P

Solution Summary: The author explains the mechanism of Claisen Condensation, wherein a proton is abstracted from the alpha -carbon and attached to the carbonyl carbon of another ester.

Concept explainers

Videos

Want to see the full answer?

Chapter 13 Solutions