Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 13.6, Problem 2TQ
Summary Introduction

To review:

The comparison of reactions catalyzed by pyruvate dehydrogenase and pyruvate formate lyase and the conditions favoring them.

Introduction:

Pyruvate lies at a crossroad of essential energy metabolic pathways. It is the final product of glycolysis and marks the start of gluconeogenesis. It can be created by alanine transamination. It can be transformed into acetyl CoA (Coenzyme A) by the pyruvate dehydrogenase complex. Acetyl CoA can join the TCA (tricarboxylic acid) cycle or act as the starting point for the synthesis of steroids, fatty acids, and ketone bodies based on the metabolic state in which it is made.

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