Chapter 13.5, Problem 1ET

Envision yourself as a physician. A mother, father, and their daughter come to you because the daughter is 16 years old and hasn’t had her first menstrual cycle, whereas all of her girlfriends started menstruating years ago. You do a Karyotype and that she is XY. Further molecular genetic testing reveals that she has a mutated androgen receptor allele on her X chromosome. The parents want to know how their daughter inherited the syndrome, why they don't have it and. If they were to have other children. If they would be androgen insensitive. How would you explain, in terms understandable to a layperson, the inheritance of androgen insensitivity and the likelihood that the parents would have another child with androgen insensitivity syndrome? Include diagrams to help them understand.