Biology: Life on Earth with Physiology (11th Edition)
Biology: Life on Earth with Physiology (11th Edition)
11th Edition
ISBN: 9780133923001
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 13.3, Problem 1CSC
Summary Introduction

To determine:’

How do altered codons affect protein structure and function in case of mutations in the CFTR gene.

Introduction:

Cystic fibrosis is the recessive genetic disorder caused by defective alleles of a gene that encodes a crucially important protein called CFTR (cystic fibrosis transmembrane conductance regulator). It occurs when a person is homozygous for defective CFTR alleles. The CFTR protein is found in the pancreas, intestine, sweat glands, and in the cells lining the airways of the lungs. Mutations in the CFTR genes affect the structure and function of the protein.

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