Essentials of Human Anatomy & Physiology Plus MasteringA&P with eText -- Access Card Package (11th Edition)
Essentials of Human Anatomy & Physiology Plus MasteringA&P with eText -- Access Card Package (11th Edition)
11th Edition
ISBN: 9780321918758
Author: Elaine N. Marieb
Publisher: PEARSON
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Chapter 13, Problem 2MC
Summary Introduction

Introduction:

The diaphragm is the primary muscle responsible for the maintenance of thoracic cavity and controls the intrathoracic pressure. The inspiration and expiration process involves the rhythmic movement of the diaphragm. These movements alter the pressure within the thoracic cage and help in respiration. This brings a change in the rates of inspiration and expiration.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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