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(a)
Interpretation:
For the given proposed transforms, it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for
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Answer to Problem 13.6P
The synthesis will proceed as planned. The forward reaction is shown below:
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side. In the target molecule, there are two functional groups present, a cyanide and hydroxyl group. In order to carry out this transform, sodium cyanide (
Thus, the proposed transform does not lead to a synthetic trap and will proceed as planned.
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
(b)
Interpretation:
For the given proposed transforms, it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for functional group transformation and considering the factors like charge stability and strength of the reagent used, one can determine whether the proposed transform leads to a synthetic trap or not.
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Answer to Problem 13.6P
The synthesis will proceed as planned. The forward reaction is shown below:
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side. In the target molecule, there are two functional groups present,
Thus, the proposed transform does not lead to a synthetic trap and will proceed as planned.
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
(c)
Interpretation:
For the given proposed transforms, it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for functional group transformation, and considering the factors like charge stability and strength of the reagent used, one can determine whether the proposed transform leads to a synthetic trap or not.
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Answer to Problem 13.6P
The synthesis will proceed as planned. The forward reaction is shown below:
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side. In the target molecule, there are two functional groups present, alkyl halide and hydroxyl group.
Thus, the proposed transform does not lead to a synthetic trap and will proceed as planned.
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
(d)
Interpretation:
For the given proposed transforms, it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for functional group transformation, and considering the factors like charge stability and strength of the reagent used, one can determine whether the proposed transform leads to the synthetic trap or not.
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Answer to Problem 13.6P
The synthesis will not proceed as planned.
The proposed synthesis is a synthetic trap, and the reaction will not proceed as planned in the forward direction.
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side while the proposed reactant molecule is on the right side. In the target molecule, there are two functional groups present, alcohol and alkyl halide. Alkyl halides are prepared from corresponding alcohols when they are treated with phosphorous bromide/chloride in an
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
(e)
Interpretation:
For the given proposed transforms, it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for functional group transformation, and considering the factors like charge stability and strength of the reagent used, one can determine whether the proposed transform leads to the synthetic trap or not.
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Answer to Problem 13.6P
The synthesis will not proceed as planned.
The proposed synthesis is a synthetic trap, and the reaction will not proceed as planned in the forward direction.
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side while the proposed reactant molecule is on the right side. In the target molecule, there are two functional groups present, ether and alkyl halide. Alkyl halides are prepared from
As the reaction does not yield the desired product, we would say that the proposed synthesis is a synthetic trap, and the reaction will not proceed as planned in the forward direction.
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
(f)
Interpretation:
For the given proposed transforms it is to be determined whether it leads to a synthetic trap (i.e. will not proceed as planned in the forward direction) or not along with the reasoning.
Concept introduction:
A particular reaction is undone by performing a transform that depends on the specific location in the target molecule where we want the changes to occur. In doing so, we may encounter synthetic traps. A synthetic trap is the proposed mechanism that prevents the reaction to occur in the forward direction as planned. From the reactions used for functional group transformation, and considering the factors like charge stability and strength of the reagent used, one can determine whether the proposed transform leads to the synthetic trap or not.
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Answer to Problem 13.6P
The synthesis will not proceed as planned.
The proposed synthesis is a synthetic trap, and the reaction will not proceed as planned in the forward direction.
Explanation of Solution
The given proposed transform is:
The target molecule is on the left side while the proposed reactant molecule is on the right side. In the target molecule, there are two functional groups present,
As the reaction does not yield the desired product, we would say that, the proposed synthesis is a synthetic trap and the reaction will not proceed as planned in the forward direction.
The possibility of the forward reaction in the proposed mechanism is determined on the basis of the functional group transformation reactions, charge stability, and strength of the reagents used.
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Chapter 13 Solutions
Organic Chemistry: Principles and Mechanisms (Second Edition)
- What would be the best choices for the missing reagents 1 and 3 in this synthesis? 1. PPh3 3 2. n-BuLi • Draw the missing reagents in the drawing area below. You can draw them in any arrangement you like. • Do not draw the missing reagent 2. If you draw 1 correctly, we'll know what it is. • Note: if one of your reagents needs to contain a halogen, use bromine. Click and drag to start drawing a structure.arrow_forwardIdentify the missing organic reactants in the following reaction: X + Y H+ two steps Note: This chemical equation only focuses on the important organic molecules in the reaction. Additional inorganic or small-molecule reactants or products (like H2O) are not shown. In the drawing area below, draw the skeletal ("line") structures of the missing organic reactants X and Y. You may draw the structures in any arrangement that you like, so long as they aren't touching. Click and drag to start drawing a structure. Х :arrow_forwardDraw the mechanism of friedel-crafts acylation using acetyl chloride of m-Xylenearrow_forward
- Don't used hand raiting and don't used Ai solution and correct answerarrow_forwardH R Part: 1/2 :CI: is a/an electrophile Part 2 of 2 Draw the skeletal structure of the product(s) for the Lewis acid-base reaction. Include lone pairs and formal charges (if applicable) on the structures. 4-7: H ö- H Skip Part Check X :C1: $ % L Fi Click and drag to start drawing a structure. MacBook Pro & ㅁ x G 0: P Add or increase positive formal cha Save For Later Submit ©2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Centearrow_forwardDraw the friedel-crafts acylation mechanism of m-Xylenearrow_forward
- Don't used hand raiting and don't used Ai solutionarrow_forward1. Base on this experimental results, how do you know that the product which you are turning in is methyl 3-nitrobenzoate(meta substituted product ) rather than either of the other two products? 2. What observation suggests that at least a small amount of one or both of the other two isomers are in the mother liquor?arrow_forwardExplain Huckel's rule.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning
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