Concept explainers
Interpretation:
The synthesis of the given target molecule from
Concept introduction:
Synthesis may be designed by thinking in the reverse direction, from the product to the starting compound, in a method called retrosynthesis. Retrosynthesis involves starting with the product and determining a suitable precursor from which it can be synthesized, without considering specific reactions. The precursor must be a simpler molecule, which may or may not have a close structural relation to the target molecule. This process is repeated until an easily available (or easily prepared) precursor is reached. Each of these steps is called a transform. A synthesis is a specific sequence of
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Check out a sample textbook solutionChapter 13 Solutions
Organic Chemistry: Principles and Mechanisms (Second Edition)
- 10. In chapter 18, we learned that benzene (the most prevalent aromatic ring) reacts with good electrophiles in electrophilic aromatic substitution (EAS) reactions. In chapter 17, we learned there are many other aromatic rings other than benzene. These other aromatic rings can participate in EAS reactions much the same way. The following is an EAS reaction with pyrrole as the starting nucleophile. Draw the complete, detailed mechanism for the formation of the given major product. Include all resonance structures in the sigma complex. BC13arrow_forwardFor the structures shown below, state the number of pi electrons present in the molecule. H H H H * H H H Number of pi electrons -6 ماتاد V H Number of pi electrons Is the molecule aromatic according to the Huckel criteria? N H If the molecule were planar, would it be antiaromatic?arrow_forwardGive handwritten answerarrow_forward
- Give detailed Solution with explanation needed..give correct answer if you not then don't give answer..I will give you upvote..draw out all of the substitution and elimination reactionsarrow_forwardAn α carbon of a ketone or aldehyde can be alkylated or halogenated under basic conditions. Recall that multiple halogenations take place under these conditions, whereas polyalkylation is generally not a concern. Suggest whyarrow_forwardWhat is the slow (rate-determining) step in any electrophilic aromatic substitution reaction? Please provide a detailed explanation.arrow_forward
- (SYN) Show how you would carry out the following synthesis from the starting material given, using any other compound containing, at most, one carbon atom. ? OH OCH3arrow_forward(please correct answer and don't use hend raiting) Propose a plausible mechanism for the followingarrow_forward(SYN) Show how to synthesize 2,4-diphenylbut-2-ene using phenylethanoic acid (phenylacetic acid) as your only source of carbon atoms.arrow_forward
- (SYN) Show how to carry out this synthesis using benzene and any alcohol as your only source of carbon.arrow_forwardGive detailed Solution with explanation neededarrow_forward(SYN) A student wants to carry out the reaction shown here. Explain the problem(s) associated with this synthesis scheme and suggest a way to carry out the transformation efficiently. 1. LDA 2. CH3I HO.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning