Brock Biology of Microorganisms (14th Edition)
Brock Biology of Microorganisms (14th Edition)
14th Edition
ISBN: 9780321897398
Author: Michael T. Madigan, John M. Martinko, Kelly S. Bender, Daniel H. Buckley, David A. Stahl, Thomas Brock
Publisher: PEARSON
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Chapter 12.7, Problem 1MQ
  • What is the difference between the core and pan genomes of a given species?
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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 12 Solutions

Brock Biology of Microorganisms (14th Edition)

Ch. 12.4 - Prob. 2MQCh. 12.4 - Prob. 3MQCh. 12.5 - How are DNA sequences obtained for phylogenetic...Ch. 12.5 - What does a phylogenetic tree depict?Ch. 12.5 - Prob. 3MQCh. 12.6 - What are the different processes that give rise to...Ch. 12.6 - What is the difference between selection and...Ch. 12.6 - In the experiment of Figure 13.12, why did the...Ch. 12.7 - What is the difference between the core and pan...Ch. 12.7 - What kind of recombination might have the greatest...Ch. 12.7 - What effects do deletions have on the evolution of...Ch. 12.8 - What is the difference between taxonomy and...Ch. 12.8 - What are some key criteria from the phylogenetic...Ch. 12.8 - How many species of Bacteria and Archaea have been...Ch. 12.9 - What class of genes is used in MLST analyses?Ch. 12.9 - How is ribotyping different from rep-PCR?Ch. 12.9 - What is FAME analysis?Ch. 12.10 - What roles do culture collections play in...Ch. 12.10 - What is the IJSEM and what taxonomic function does...Ch. 12.10 - Why might viable cell cultures be of more use in...Ch. 12 - Prob. 1RQCh. 12 - Prob. 2RQCh. 12 - Prob. 3RQCh. 12 - What is the endosymbiotic hypothesis for the...Ch. 12 - Prob. 5RQCh. 12 - REVIEW QUESTIONS 6. What major physiological and...Ch. 12 - Prob. 7RQCh. 12 - Prob. 8RQCh. 12 - Prob. 9RQCh. 12 - What is the difference between a gene tree and an...Ch. 12 - Prob. 11RQCh. 12 - Prob. 12RQCh. 12 - What is fitness? To what degree does fitness...Ch. 12 - What are some processes that influence the content...Ch. 12 - Prob. 15RQCh. 12 - What is the "species problem" and why is the...Ch. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - Prob. 19RQCh. 12 - Prob. 20RQCh. 12 - Prob. 21RQCh. 12 - Compare and contrast the physical and chemical...Ch. 12 - For the following sequences, construct the...Ch. 12 - Imagine that you have been given several bacterial...Ch. 12 - Imagine that you have discovered a new form of...
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License