Fundamentals of Statistics (5th Edition)
Fundamentals of Statistics (5th Edition)
5th Edition
ISBN: 9780134508306
Author: Michael Sullivan III
Publisher: PEARSON
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Chapter 12.2, Problem 21AYU

Putting It Together: Women, Aspirin, and Heart Attacks In a famous study by the Physicians Health Study Group from Harvard University from the late 1980s, 22,000 healthy male physicians were randomly divided into two groups; half the physicians took aspirin every other day, and the others were given a placebo. Of the physicians in the aspirin group, 104 heart attacks occurred; of the physicians in the placebo group, 189 heart attacks occurred. The results were statistically significant, which led to the advice that males should take an aspirin every other day in the interest of reducing the chance of having a heart attack. Does the same advice apply to women? In a randomized, placebo-controlled study, 39,876 healthy women 45 years of age or older were randomly divided into two groups. The women in group 1 received 100 mg of aspirin every other day; the women in group 2 received a placebo every other day. The women were monitored for 10 years to determine if they experienced a cardiovascular event (such as heart attack or stroke). Of the 19,934 in the aspirin group, 477 experienced a heart attack. Of the 19,942 women in the placebo group, 522 experienced a heart attack.

Source: Paul M. Ridker et al. “A Randomized Trial of Low-Dose Aspirin in the Primary Prevension of Cardiovascular Disease in Woman.” New England Journal of Medicine 352: 1293–1304.

  1. a. What is the population being studied? What is the sample?
  2. b. What is the response variable? Is it qualitative or quantitative?
  3. c. What are the treatments?
  4. d. What type of experimental design is this?
  5. e. How does randomization deal with the explanatory variables that were not controlled in the study?
  6. f. Determine whether the proportion of cardiovascular events in each treatment group is different using a two-sample Z-test for comparing two proportions. Use the α = 0.05 level of significance. What is the test statistic?
  7. g. Determine whether the proportion of cardiovascular events in each treatment group is different using a chi-square test for homogeneity of proportions. Use the α = 0.05 level of significance. What is the test statistic?
  8. h. Square the test statistic from part (f) and compare it to the test statistic from part (g). What do you conclude?
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Chapter 12 Solutions

Fundamentals of Statistics (5th Edition)

Ch. 12.1 - Applying the Concepts 11. NW Plain MMs According...Ch. 12.1 - Peanut MMs According to the manufacturer of MMs,...Ch. 12.1 - Prob. 13AYUCh. 12.1 - Prob. 14AYUCh. 12.1 - Always Wear a Helmet The National Highway Traffic...Ch. 12.1 - Religion in Congress Is the religious make-up of...Ch. 12.1 - Does It Matter Where I Sit? Does the location of...Ch. 12.1 - Racial Profiling On January 1, 2004, it became...Ch. 12.1 - Prob. 19AYUCh. 12.1 - Prob. 20AYUCh. 12.1 - Prob. 21AYUCh. 12.1 - Is the Die Loaded? A player in a craps game...Ch. 12.1 - Grade Distributions At Joliet Junior College, the...Ch. 12.1 - Population Shift An urban economist wonders if the...Ch. 12.1 - Prob. 25AYUCh. 12.1 - Living Alone? In 2000, 25.8% of Americans 15 years...Ch. 12.1 - Putting It Together: The V-2 Rocket in London In...Ch. 12.1 - Putting It Together: Weldons Dice On February 2,...Ch. 12.1 - Buying a New Car How much does the typical person...Ch. 12.1 - Why is goodness of fit a good choice for the title...Ch. 12.1 - Explain why chi-square goodness-of-fit tests are...Ch. 12.1 - Prob. 32AYUCh. 12.2 - True or False: The expected frequencies in a...Ch. 12.2 - In a chi-square test for ____ of proportions, we...Ch. 12.2 - The following table contains observed values and...Ch. 12.2 - The table in the next column contains observed...Ch. 12.2 - Prob. 5AYUCh. 12.2 - Prob. 6AYUCh. 12.2 - NW Family Structure and Sexual Activity A...Ch. 12.2 - Prenatal Care An obstetrician wants to learn...Ch. 12.2 - Health and Happiness Are health and happiness...Ch. 12.2 - Health and Education Does amount of education play...Ch. 12.2 - Social Well-Being and Obesity The Gallup...Ch. 12.2 - Profile of Smokers The following data represent...Ch. 12.2 - Efficacy of e-Cigs Do electronic cigarettes assist...Ch. 12.2 - Celebrex Celebrex, a drug manufactured by Pfizer,...Ch. 12.2 - NW Whats in a Word? In a recent survey conducted...Ch. 12.2 - Whats in a Word? Part II In a recent survey...Ch. 12.2 - Dropping a Course A survey was conducted at a...Ch. 12.2 - Prob. 18AYUCh. 12.2 - Prob. 19AYUCh. 12.2 - Prob. 20AYUCh. 12.2 - Putting It Together: Women, Aspirin, and Heart...Ch. 12.2 - Homeruns Go to...Ch. 12.2 - Explain the differences between the chi-square...Ch. 12.2 - Why does the test for homogeneity follow the same...Ch. 12.3 - Suppose a least-squares regression line is given...Ch. 12.3 - Prob. 2AYUCh. 12.3 - Prob. 3AYUCh. 12.3 - Prob. 4AYUCh. 12.3 - Prob. 5AYUCh. 12.3 - Prob. 6AYUCh. 12.3 - Prob. 7AYUCh. 12.3 - Prob. 8AYUCh. 12.3 - Prob. 9AYUCh. 12.3 - Prob. 10AYUCh. 12.3 - An Unhealthy Commute The following data represent...Ch. 12.3 - Credit Scores An economist wants to determine the...Ch. 12.3 - Height versus Head Circumference A pediatrician...Ch. 12.3 - Hurricanes The data in the next column represent...Ch. 12.3 - Concrete As concrete cures, it gains strength. The...Ch. 12.3 - Tar and Nicotine Every year the Federal Trade...Ch. 12.3 - Invest in Education Go to...Ch. 12.3 - American Black Bears In 1969, Dr. Michael R....Ch. 12.3 - CEO Performance (Refer to Problem 31 in Section...Ch. 12.3 - Bear Markets (Refer to Problem 32. Section 4.1) A...Ch. 12.3 - Age versus HDL Cholesterol A doctor wanted to...Ch. 12.3 - Prob. 22AYUCh. 12.3 - Influential Observations Zillow.com is a site that...Ch. 12.3 - Why is it important to perform graphical as well...Ch. 12.3 - Prob. 25AYUCh. 12.3 - Why is it desirable to have the explanatory...Ch. 12.4 - Intervals constructed about the predicted value of...Ch. 12.4 - Prob. 2AYUCh. 12.4 - Prob. 3AYUCh. 12.4 - Using the sample data from Problem 6 in Section...Ch. 12.4 - Prob. 5AYUCh. 12.4 - Prob. 6AYUCh. 12.4 - Prob. 7AYUCh. 12.4 - Prob. 8AYUCh. 12.4 - Prob. 9AYUCh. 12.4 - Prob. 10AYUCh. 12.4 - Prob. 11AYUCh. 12.4 - Tar and Nicotine Use the results of Problem 16 in...Ch. 12.4 - Prob. 13AYUCh. 12.4 - Prob. 14AYUCh. 12.4 - CEO Performance Use the results of Problem 19 from...Ch. 12.4 - Prob. 16AYUCh. 12.4 - Prob. 17AYUCh. 12 - Roulette Wheel A pit boss suspects that a roulette...Ch. 12 - Prob. 2RECh. 12 - Titanic With 20% of men, 74% of women, and 52% of...Ch. 12 - Prob. 4RECh. 12 - Prob. 5RECh. 12 - Prob. 6RECh. 12 - Seat Choice and GPA A biology professor wants to...Ch. 12 - Apartments The following data represent the square...Ch. 12 - Calories versus Sugar The following data represent...Ch. 12 - A pit boss is concerned that a pair of dice being...Ch. 12 - Prob. 2CTCh. 12 - The Harris Poll asked a random sample of adult...Ch. 12 - Prob. 4CTCh. 12 - Prob. 5CTCh. 12 - Prob. 6CTCh. 12 - Crickets make a chirping noise by sliding their...Ch. 12 - The following data represent the height (inches)...Ch. 12 - A researcher believes that as age increases, the...Ch. 12 - CASE STUDY Feeling Lucky? Well, Are You? In fiscal...
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