BIOCHEMISTRY
BIOCHEMISTRY
9th Edition
ISBN: 2818440090622
Author: BERG
Publisher: MAC HIGHER
Question
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Chapter 12, Problem 1P
Interpretation Introduction

Interpretation:

The number of phospholipid molecules in 1µm2 of the bilayer membrane needs to be calculated if phospholipid molecule occupies 70 Å2 of surface area.

Concept introduction:

Lipids are fatty molecules that occupy 50% of the mass of the cell membrane. Most of the membrane lipids are phospholipids.

Expert Solution & Answer
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Answer to Problem 1P

There are 2.86×106 phospholipid molecules in 1µm2of the bilayer membrane.

Explanation of Solution

Lipid bilayers are two-dimensional fluids which are a universal basis of the cell membrane.

Membrane lipids and proteins move along the membrane.

Lateral diffusion for the phospholipids is very rapid.

Phospholipid moves by 1m2 in one sec=molecule diffuses by 2m in one sec.

Molecule travels from one end of the bacterial cell to another in one sec.

Human red blood cells can be passed in 12 sec.

Each leaflet of the bilayer contains 1.43×106 molecules.

There are two leaflets in the bilayer membrane.

Thus, in the bilayer membrane, the number of molecules are:

  = 2×1.43×106

  = 2.86×106

Hence, there are 2.86×106 molecules in the 1µm2 of the bilayer membrane.

Conclusion

The phospholipid in two layers called a phospholipid bilayer. Each leaflet of the membrane has 1.43×106 molecule hence, the bilayer membrane consists of 2.86×106 molecules.

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