HUMAN HEREDITY (LL)-W/MINDTAP ACCESS
11th Edition
ISBN: 9781305717022
Author: Cummings
Publisher: CENGAGE L
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 12, Problem 18QP
You are in charge of a new gene therapy clinic. Two cases have been referred to you for review and possible therapy.
Case 1. A mutation in the promoter of a proto-oncogene causes the gene to make too much of its normal product, a receptor protein that promotes cell division. The uncontrolled cell division has caused cancer.
Case 2. A mutation in an exon of a tumor-suppressor gene makes this gene nonfunctional. The product of this gene normally suppresses cell division. The mutant gene cannot suppress cell division, and this has led to cancer. What treatment options can you suggest for each case?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Answer Question 1-9
Ex: Mr. Mandarich wanted to see if the color of light shined on a planthad an effect on the number of leaves it had. He gathered a group ofthe same species of plants, gave them the same amount of water, anddid the test for the same amount of time. Only the color of light waschanged.
IV:DV:Constants:Control Gr:
ethical considerations in medical imaging
Chapter 12 Solutions
HUMAN HEREDITY (LL)-W/MINDTAP ACCESS
Ch. 12.10 - If improved diagnostic tests are developed from...Ch. 12.10 - If you had cancer, would you donate tissue samples...Ch. 12.10 - Prob. 1GRCh. 12.10 - Another model, the random model, proposes that any...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Theodor Boveri predicted that malignancies would...Ch. 12 - Distinguish between a familial and a sporadic...Ch. 12 - Benign tumors: a. are noncancerous growths that do...
Ch. 12 - Prob. 4QPCh. 12 - Prob. 5QPCh. 12 - Prob. 6QPCh. 12 - Prob. 7QPCh. 12 - Prob. 8QPCh. 12 - What is the difference between a proto-oncogene...Ch. 12 - Distinguish between dominant inheritance and...Ch. 12 - Describe the likelihood of developing bilateral...Ch. 12 - Prob. 12QPCh. 12 - The search for the BRCA1 breast cancer gene...Ch. 12 - What are the roles of cellular proto-oncogenes,...Ch. 12 - Which of the following mutations will result in...Ch. 12 - Prob. 16QPCh. 12 - The following family has a history of inherited...Ch. 12 - You are in charge of a new gene therapy clinic....Ch. 12 - Prob. 19QPCh. 12 - Can you postulate a reason or reasons why children...Ch. 12 - Prob. 21QPCh. 12 - In Section 12-1, Julie is concerned that she may...Ch. 12 - Prob. 23QPCh. 12 - What are some factors that epidemiologists have...Ch. 12 - Smoking cigarettes has been shown to be associated...Ch. 12 - Prob. 26QPCh. 12 - Studies have shown that there are significant...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Please correct answer and don't used hand raiting and don't used Ai solutionarrow_forward2. In one of the reactions of the citric acid cycle, malate is oxidized to oxaloacetate. When this reaction is considered in isolation, a small amount of malate remains and is not oxidized. The best term to explain this is a. enthalpy b. entropy c. equilibrium d. free energy e. loss of energyarrow_forward18. The citric acid cycle takes place in a. the chloroplasts b. the cytosol c. the inner mitochondrial membrane d. between the two mitochondrial membranes e. the mitochondrial matrix 40 WILarrow_forward
- 8. Most reactions of anaerobic respiration are similar to a. aerobic respiration b. photosynthesis c. lactic acid fermentation d. alcoholic fermentation e. both c and darrow_forward12. Which of the following molecules can absorb light? a. Pigments b. Chlorophyll c. Rhodopsin d. Carotenoids e. All of the abovearrow_forwardWhich of the following proteins or protein complexes is directly required for the targeting of mitochondrial inner membrane multipass proteins, such as metabolite transporters, whose signal sequence is normally not cleaved after import? OA. TIM22 OB. TIM23 C. OXA OD. Mia40 OE SAMarrow_forward
- QUESTION 9 An animal cell has been wounded and has a small rupture in its plasma membrane. Which of the following is more likely to happen next? OA. The cell rapidly cleaves by cytokinesis. OB. The rate of receptor-mediati endocytosis is increased. OC. The rate of exocytosis is increased. OD. The rate of pinocytosis is increased.arrow_forwardFor the a subunit of a trimeric G protein, A. a G-protein-coupled receptor GPCR) acts as a guanine nucleotide exchange factor (GEF), whereas a regulator of G protein signaling (RGS) can act as a GTPase-activating protein (GAP). B. a GPCR acts as a GAP, whereas an RGS can act as a GEF. C. both a GPCR and an RGS can act as a GEF. O D. both a GPCR and an RGS can act as a GAP OE. None of the above.arrow_forwardA cell expresses a transmembrane protein that is cleaved at the plasma membrane to release an extracellular fragment. The fragment binds to receptor proteins on nearby cells and activates signaling pathways resulting in altered gene expression patterns in the cells. What form of intercellular signaling does this represent? OA. Contact-dependent signaling B. Paracrine signaling OC. Synaptic signaling D. Endocrine signaling E. Autocrine signalingarrow_forward
- Which of the following drive nuclearly encoded proteins import into the mitochondrial matrix? OA. ATP hydrolysis OB. Membrane Potential OC. K+ Ions OD. A and B OE. None of the abovearrow_forwardWhich of the following statements is true regarding Cholesterol import into the cell? OA. It is transported within LDL B. Receptor mediated endocytosis is involved OC. Release of cholesterol occurs in the Lysosome D. All of the above are true statements OE. None of the above are true statementsarrow_forwardIn which of the following schematic drawings of signaling pathways does the activation of the receptor lead to gene expression? Activating and inhibitory steps are indicated with (+) and (-), respectively. OA OB ㅇㅂㅇㅂㅇㅁ (+) Gene Expression Activated Signaling proteins Transcription receptor activator Bl D Gene Expression Gene Expression ㅁㅁㅇ Gene Expression Gene Expressionarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Lifetime Physical Fitness & WellnessHealth & NutritionISBN:9781337677509Author:HOEGERPublisher:Cengage
Biology: The Unity and Diversity of Life (MindTap...BiologyISBN:9781305073951Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa StarrPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Lifetime Physical Fitness & Wellness
Health & Nutrition
ISBN:9781337677509
Author:HOEGER
Publisher:Cengage
Biology: The Unity and Diversity of Life (MindTap...
Biology
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license