Anatomy & Physiology
5th Edition
ISBN: 9780321861580
Author: Marieb, Elaine N.
Publisher: Pearson College Div
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Chapter 11, Problem 22RQ
The effects of neurotransmitter binding are very brief. Explain.
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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
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According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."
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You have a bacterial strain with the CMU operon:
a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a
kinase and regulator corresponding to a two-component system. The cmu operon is
activated when Pep 1 is added to the growth media.
Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon.
Pep1 cmu-kinase cmu-regulator
You also have these genetic components in other strains:
b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a
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c) the gene cl (a repressor).
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Chapter 11 Solutions
Anatomy & Physiology
Ch. 11 - What is meant by integration, and does it...Ch. 11 - Which subdivision of the PNS is involved in (a)...Ch. 11 - Which type of neuroglia controls the extracellular...Ch. 11 - Which two types of neuroglia form insulating...Ch. 11 - MAKING CONNECTIONS Which part of the neuron is its...Ch. 11 - How does a nucleus within the brain differ from a...Ch. 11 - How is a myelin sheath formed in the CNS, and what...Ch. 11 - Which structural and functional type of neuron is...Ch. 11 - For an open channel, what factors determine in...Ch. 11 - For which cation is there the greatest amount of...
Ch. 11 - Which is bigger, a graded potential or an action...Ch. 11 - An action potential does not get smaller as it...Ch. 11 - Why does a myelinated axon conduct action...Ch. 11 - If an axon receives two stimuli close together in...Ch. 11 - What structure joins two neurons at an electrical...Ch. 11 - Events at a chemical synapse usually involve...Ch. 11 - Which ions flow through chemically gated channels...Ch. 11 - Prob. 18CYUCh. 11 - Prob. 19CYUCh. 11 - Why is cyclic AMP called a second messenger?Ch. 11 - Which types of neural circuits would give a...Ch. 11 - Prob. 22CYUCh. 11 - What pattern of neural processing occurs when we...Ch. 11 - Which of the following structures is not part of...Ch. 11 - Match the names of the supporting cells found in...Ch. 11 - Prob. 3RQCh. 11 - Assume that an EPSP is being generated on the...Ch. 11 - The velocity of nerve impulse conduction is...Ch. 11 - Chemical synapses are characterized by all of the...Ch. 11 - Biogenic amine neurotransmitters include all but...Ch. 11 - Prob. 8RQCh. 11 - Inhibition of acetylcholinesterase by poisoning...Ch. 11 - Prob. 10RQCh. 11 - An IPSP is inhibitory because (a) it...Ch. 11 - Identify the neuronal circuits described by...Ch. 11 - Explain both the anatomical and functional...Ch. 11 - (a) Describe the composition and function of the...Ch. 11 - (a) What is myelin? (b) How does the myelination...Ch. 11 - (a) Contrast unipolar, bipolar, and multipolar...Ch. 11 - What is the polarized membrane state? How is it...Ch. 11 - Describe the events that must occur to generate an...Ch. 11 - Prob. 19RQCh. 11 - (a) Explain the difference between an EPSP and an...Ch. 11 - Since at any moment a neuron is likely to have...Ch. 11 - The effects of neurotransmitter binding are very...Ch. 11 - Prob. 23RQCh. 11 - Prob. 24RQCh. 11 - Elaine Sawyer, 35, was on her way to the local...Ch. 11 - Elaine Sawyer, 35, was on her way to the local...Ch. 11 - Elaine Sawyer, 35, was on her way to the local...Ch. 11 - Elaine Sawyer, 35, was on her way to the local...Ch. 11 - Elaine Sawyer, 35, was on her way to the local...
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- You have identified a new species of a Gram-positive bacteria. You would like to screen their genome for all proteins that are covalently linked to the cell wall. You have annotated the genome, so that you identified all the promoters, operons, and genes sequences within the operons. Using these features, what would you screen for to identify a set of candidates for proteins covalently linked to the bacterial cell wall.arrow_forwardBelow is a diagram from a genomic locus of a bacterial genome. Each arrow represents a coding region, and the arrowheads indicate its orientation in the genome. The numbers are randomly assigned. Draw the following features on the diagram, and explain your rationale for each feature: 10 12 合會會會會長 6 a) Expected transcriptions, based on known properties of bacterial genes and operons. How many proteins are encoded in each of the transcripts? b) Location of promoters (include rationale) c) Location of transcriptional terminators (include rationale) d) Locations of Shine-Dalgarno sequences (include rationale)arrow_forwardSample excuse letter in school class for the reasons of headaches and dysmenorrhea caused by menstrual cyclearrow_forward
- How do the muscles on the foot work to balance on an ice skate, specifically the triangle of balance and how does it change when balancing on an ice skate? (Refer to anatomy, be specific)arrow_forwardWhich of the following is NOT an example of passive immunization? A. Administration of tetanus toxoid B. Administration of hepatitis B immunoglobulin C. Administration of rabies immunoglobulin D. Transfer of antibodies via plasma therapyarrow_forwardTranscription and Translation 1. What is the main function of transcription and translation? (2 marks) 2. How is transcription different in eukaryotic and prokaryotic cells? (2 marks) 3. Explain the difference between pre-mRNA and post-transcript mRNA. (2 marks) 4. What is the function of the following: (4 marks) i. the cap ii. spliceosome iii. Poly A tail iv. termination sequence 5. What are advantages to the wobble feature of the genetic code? (2 marks) 6. Explain the difference between the: (3 marks) i. A site & P site ii. codon & anticodon iii. gene expression and gene regulation 7. Explain how the stop codon allows for termination. (1 mark) 8. In your own words, summarize the process of translation. (2 marks)arrow_forward
- In this activity you will research performance enhancers that affect the endocrine system or nervous system. You will submit a 1 page paper on one performance enhancer of your choice. Be sure to include: the specific reason for use the alleged results on improving performance how it works how it affect homeostasis and improves performance any side-effects of this substancearrow_forwardNeurons and Reflexes 1. Describe the function of the: a) dendrite b) axon c) cell body d) myelin sheath e) nodes of Ranvier f) Schwann cells g) motor neuron, interneuron and sensory neuron 2. List some simple reflexes. Explain why babies are born with simple reflexes. What are they and why are they necessary. 3. Explain why you only feel pain after a few seconds when you touch something very hot but you have already pulled your hand away. 4. What part of the brain receives sensory information? What part of the brain directs you to move your hand away? 5. In your own words describe how the axon fires.arrow_forwardMutations Here is your template DNA strand: CTT TTA TAG TAG ATA CCA CAA AGG 1. Write out the complementary mRNA that matches the DNA above. 2. Write the anticodons and the amino acid sequence. 3. Change the nucleotide in position #15 to C. 4. What type of mutation is this? 5. Repeat steps 1 & 2. 6. How has this change affected the amino acid sequence? 7. Now remove nucleotides 13 through 15. 8. Repeat steps 1 & 2. 9. What type of mutation is this? 0. Do all mutations result in a change in the amino acid sequence? 1. Are all mutations considered bad? 2. The above sequence codes for a genetic disorder called cystic fibrosis (CF). 3. When A is changed to G in position #15, the person does not have CF. When T is changed to C in position #14, the person has the disorder. How could this have originated?arrow_forward
- hoose a scientist(s) and research their contribution to our derstanding of DNA structure or replication. Write a one page port and include: their research where they studied and the time period in which they worked their experiments and results the contribution to our understanding of DNA cientists Watson & Crickarrow_forwardhoose a scientist(s) and research their contribution to our derstanding of DNA structure or replication. Write a one page port and include: their research where they studied and the time period in which they worked their experiments and results the contribution to our understanding of DNA cientists Watson & Crickarrow_forward7. Aerobic respiration of a protein that breaks down into 12 molecules of malic acid. Assume there is no other carbon source and no acetyl-CoA. NADH FADH2 OP ATP SLP ATP Total ATP Show your work using dimensional analysis here: 3arrow_forward
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