Chapter 10.8, Problem 19P

Interpretation Introduction

Interpretation:

The deuterium kinetic isotope effect has to be determined for the reactions.

Concept Introduction:

Elimination Reaction: It is just reverse reaction of addition where substituent from the given molecule is removed via E1 (the reaction depends only on the substrate involved in the reaction) or E2 (the reaction depends on both of the substituents in the reaction) mechanism.

Elimination reaction of an alkyl halide results in the formation of an alkene.

Carbocation: it is carbon ion that bears a positive charge on it. The increasing stability order of carbocation is as follows,

Primary carbocation < secondary carbocation < tertiary carbocation

Deuterium kinetic isotope effect can be expressed as,

$\text{Deuterium kinetic isotope effect}\text{=}\frac{\text{Rate constant for reactant}\text{containing}\text{hydrogen,}{\text{k}}_{\text{H}}}{\text{Rate constant for reactant}\text{containing}\text{deuterium,}{\text{k}}_{\text{D}}}$