Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Question
Chapter 10, Problem 61TQ
Summary Introduction
To review:
The inhibition of oxidative phosphorylation by rotenone that can take place when the substrate is pyruvate but not when succinate is used.
Introduction:
The oxidative phosphorylation is the mechanism by which the conservation of the adenosine triphosphate (ATP) generated by the electron transport chain (ETC) takes place due to the phosphorylation of adenosine diphosphate (ADP). There are many inhibitors of the ETC like antimycin A, rotenone, amyta, lnd azide. They can be used to determine the correct order of the ETC.
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Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvate dehydrogenase complex, resulting in acetyl-CoA and CO2. Provide the mechanism for this reaction utilizing the TPP cofactor. Include the roles of all cofactors.
Chapter 10 Solutions
Biochemistry, The Molecular Basis of Life, 6th Edition
Ch. 10 - Prob. 1QCh. 10 - Prob. 2QCh. 10 - Prob. 3QCh. 10 - Prob. 4QCh. 10 - Prob. 5QCh. 10 - Prob. 6QCh. 10 - Prob. 7QCh. 10 - Prob. 8QCh. 10 - Prob. 1RQCh. 10 - Prob. 2RQ
Ch. 10 - Prob. 3RQCh. 10 - Prob. 4RQCh. 10 - Prob. 5RQCh. 10 - Prob. 6RQCh. 10 - Prob. 7RQCh. 10 - Prob. 8RQCh. 10 - Prob. 9RQCh. 10 - Prob. 10RQCh. 10 - Prob. 11RQCh. 10 - Prob. 12RQCh. 10 - Prob. 13RQCh. 10 - Prob. 14RQCh. 10 - Prob. 15RQCh. 10 - Prob. 16RQCh. 10 - Prob. 17RQCh. 10 - Prob. 18RQCh. 10 - Prob. 19RQCh. 10 - Prob. 20RQCh. 10 - Prob. 21RQCh. 10 - Prob. 22RQCh. 10 - Prob. 23RQCh. 10 - Prob. 24RQCh. 10 - Prob. 25RQCh. 10 - Prob. 26RQCh. 10 - Prob. 27RQCh. 10 - Prob. 28RQCh. 10 - Prob. 29RQCh. 10 - Prob. 30RQCh. 10 - Prob. 31RQCh. 10 - Prob. 32RQCh. 10 - Prob. 33RQCh. 10 - Prob. 34RQCh. 10 - Prob. 35FBCh. 10 - Prob. 36FBCh. 10 - Prob. 37FBCh. 10 - Prob. 38FBCh. 10 - Prob. 39FBCh. 10 - Prob. 40FBCh. 10 - Prob. 41FBCh. 10 - Prob. 42FBCh. 10 - Prob. 43FBCh. 10 - Prob. 44FBCh. 10 - Prob. 45SACh. 10 - Prob. 46SACh. 10 - Prob. 47SACh. 10 - Prob. 48SACh. 10 - Prob. 49SACh. 10 - Prob. 50TQCh. 10 - Prob. 51TQCh. 10 - Prob. 52TQCh. 10 - Prob. 53TQCh. 10 - Prob. 54TQCh. 10 - Prob. 55TQCh. 10 - Prob. 56TQCh. 10 - Prob. 57TQCh. 10 - Prob. 60TQCh. 10 - Prob. 61TQCh. 10 - Prob. 62TQCh. 10 - Prob. 63TQCh. 10 - Prob. 64TQCh. 10 - Prob. 65TQCh. 10 - Prob. 66TQ
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