Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 10, Problem 20P
In the human immune system, so-called B cells can make more than a billion different types of antibody molecules that protect us from infection. However, our genomes have only three genes that encode the polypeptides found in antibodies. What experiments could you perform to determine what kind of combinatorial events occur at the DNA level (V-D-J joining) and RNA level (alternative splicing) for any of these genes?
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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27
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Chapter 10 Solutions
Genetics: From Genes to Genomes
Ch. 10 - Prob. 1PCh. 10 - List three independent techniques you could use to...Ch. 10 - Figure 10.2a has numbers indicating the...Ch. 10 - Which of the enzymes from the following list would...Ch. 10 - Prob. 5PCh. 10 - a. What sequence information about a gene is...Ch. 10 - Why do geneticists studying eukaryotic organisms...Ch. 10 - Consider three different kinds of human libraries:...Ch. 10 - The human genome has been sequenced, but we still...Ch. 10 - This problem investigates issues encountered in...
Ch. 10 - For the sake of simplicity, Fig. 10.4 omitted one...Ch. 10 - Give two different reasons for the much higher...Ch. 10 - Using a cDNA library, you isolated two different...Ch. 10 - The figure that follows shows part of a modified...Ch. 10 - In Problem 14, cDNAs F and G could not be found in...Ch. 10 - Fig. 10.10 presents a model for exon shuffling in...Ch. 10 - An interesting phenomenon found in vertebrate DNA...Ch. 10 - a. If you found a zinc-finger domain which...Ch. 10 - Prob. 19PCh. 10 - In the human immune system, so-called B cells can...Ch. 10 - Chimpanzees have a set of hemoglobin genes very...Ch. 10 - Complete genome sequences indicate that the human...Ch. 10 - On your computers browser, view the page accessed...Ch. 10 - Prob. 24PCh. 10 - Prob. 25PCh. 10 - Certain individuals with mild forms of...Ch. 10 - The 1 and 2 genes in humans are identical in their...Ch. 10 - Prob. 28P
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- examples of synamtomorphy.arrow_forwardE. Bar Graph Use the same technique to upload the completed image. We will use a different type of graph to derive additional information from the CO2 data (Fig A1.6.2) 1. Calculate the average rate of increase in COz concentration per year for the time intervals 1959-1969, 1969- 1979, etc. and write the results in the spaces provided. The value for 1959-1969 is provided for you as an example. 2. Plot the results as a bar graph. The 1959-1969 is plotted for you. 3. Choose the graph that looks the most like yours A) E BAR GRAPH We will use a different type of graph to derive additional information from the CU, data (rig. nive). Average Yearly Rate of Observatory, Hawall interval Rate of increase per year 1959-1969 0.9 1969-1979 1979-1989 1989-1999 1999-2009 Figure A1.6.2 1999-2009 *- mrame -11- -n4 P2 جية 1989-1999 1979-1989 1969-1979 1959-1969 This bar drawn for you as an example 1.0 CO, Average Increase/Year (ppmv) B) E BAR GRAPH We will use a different type of graph to derive…arrow_forwardUse the relationships you just described to compute the values needed to fill in the blanks in the table in Fig A1.4.1 depth (a) 1.0 cml 0.7 cml cm| base dimensions (b, c)| 1.0 cm| 1.0 cm| 1.0 cm 1.0 cm| 1.0 cm| 1.0 cm volume (V) 1.0_cm' cm'| cm'| density (p) 1.0 g/cm'| 1.0 g/cm 1.0 g/cm' mass (m)| 0.3 g Column 1: depth at 1.0 cm volume mass Column 2: depth at 0.7 cm volume mass Column 3: unknown depth depth volumearrow_forward
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- Draw a gram negative bacterial cell below. Your cell should have the following parts, labeled: A bacillus shape Fimbriae Amphitrichous flagella 2 membranes (outer and inner) The outer membrane should have lipopolysaccharide (LPS) with lipid A and O antigens Periplasmic space The thin peptidoglycan cell wall between the 2 membranes A nucleoid Ribosomes Inclusionsarrow_forwardBacterial species Cell wall type Example: S. mitis Gram positive S. epidermidis H. pylori M. bovis S. marcescens Shape and arrangement Coccus, streptococcus Drawing 0000000arrow_forwardDraw a gram positive bacterial cell below. Your cell should have the following parts, labeled: A coccus shape A capsule The gram positive cell wall should have the peptidoglycan labeled, as well as its component parts (NAM, NAG, and teichoic acid) A cell membrane Fimbriae A nucleoid Ribosomes Inclusionsarrow_forward
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