Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 10, Problem 9P
The human genome has been sequenced, but we still don’t have an accurate count of the number of genes. Why not?
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Why do scientists want to sequence the human genome?
When the human genome sequence was finally completed, scientists were surprised to discover that the genome contains far fewer genes than expected. How many genes are present in the human genome? Scientists have also found that there are many more different kinds of proteins in the human cells that there are different genes in the genome. How can this be explained?
The human genome project was an international effort to completely map the all of the genes of humans. The
first information on the human genome generated from this endeavor was published in 2000 and the full
sequence was published in 2003. Since then, estimates of the rumber of genes in the human genome have
steadily declined, and it is now though that there are about 20,500 genes in the human genome, but the
exact number is yet to be determined.
Since we have known the sequence of the human genome for almost two decades, why are scientists still not
sure of the total number of genes contained within the human genome? In other words, why is it taking so
long to determine the number of genes humans have?
Chapter 10 Solutions
Genetics: From Genes to Genomes
Ch. 10 - Prob. 1PCh. 10 - List three independent techniques you could use to...Ch. 10 - Figure 10.2a has numbers indicating the...Ch. 10 - Which of the enzymes from the following list would...Ch. 10 - Prob. 5PCh. 10 - a. What sequence information about a gene is...Ch. 10 - Why do geneticists studying eukaryotic organisms...Ch. 10 - Consider three different kinds of human libraries:...Ch. 10 - The human genome has been sequenced, but we still...Ch. 10 - This problem investigates issues encountered in...
Ch. 10 - For the sake of simplicity, Fig. 10.4 omitted one...Ch. 10 - Give two different reasons for the much higher...Ch. 10 - Using a cDNA library, you isolated two different...Ch. 10 - The figure that follows shows part of a modified...Ch. 10 - In Problem 14, cDNAs F and G could not be found in...Ch. 10 - Fig. 10.10 presents a model for exon shuffling in...Ch. 10 - An interesting phenomenon found in vertebrate DNA...Ch. 10 - a. If you found a zinc-finger domain which...Ch. 10 - Prob. 19PCh. 10 - In the human immune system, so-called B cells can...Ch. 10 - Chimpanzees have a set of hemoglobin genes very...Ch. 10 - Complete genome sequences indicate that the human...Ch. 10 - On your computers browser, view the page accessed...Ch. 10 - Prob. 24PCh. 10 - Prob. 25PCh. 10 - Certain individuals with mild forms of...Ch. 10 - The 1 and 2 genes in humans are identical in their...Ch. 10 - Prob. 28P
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- If you were offered the chance to have the genome of your newborn sequenced at a cost of 1,000, would you do so?arrow_forwardWhat does the future hold for genomes? How will they be different in 100, 1,000, 1 million, or 1 billion years? Make this a long discussion.arrow_forwardIf only part of the genome contains genes, why sequence the whole thing?arrow_forward
- What exactly is a genome?arrow_forwardClearly, all humans have variations in their DNA sequences. How is it possible to sequence the human genome if every individual is unique? How was the diversity of the human genome addressed?arrow_forward7) The Human Genome project cost billions of dollars to complete. What was it and do you think it was worth the cost? Use at least two lines of reasoning to support your opinion.arrow_forward
- What does it mean to sequence a genome?arrow_forwardA large portion of the human genome is transposons. Collectively, they are most likely: A) an equal mix of DNA and retrotransposons B) mostly DNA transposons because they are found in DNA C) mostly retrotransposons because they copy themselves each time they move D) mostly DNA transposons because they can cut themselves outarrow_forwardA large public and private effort went into sequencing the human genome. What did this project hope to accomplish; how did emerging technology assist the project (ie recombinant DNA, super-computing, automated sequencing), was it successful and what is the usefulness of what was learned in this massive effort?arrow_forward
- What is the significance of mapping the human genome?arrow_forwardIn a study showing that approximately 10% of protein-coding genes are essential for Cell survival .This translates into which of the following number of essential genes in the human genome .a)100 b) 500 c)1000 d)2000arrow_forwardIf you were to sequence a human genome today, how would the sequencing differ from that done during the Human Genome Project? Choose only the best answer. You would still use Sanger sequencing. You would still assemble the sequencing reads into a genome using bioinformatics. You still need to clone the DNA fragments prior to sequencing them. All three of the other statements are true.arrow_forward
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