Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 10, Problem 9P

The human genome has been sequenced, but we still don’t have an accurate count of the number of genes. Why not?

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Why do scientists want to sequence the human genome?
When the human genome sequence was finally completed, scientists were surprised to discover that the genome contains far fewer genes than expected. How many genes are present in the human genome? Scientists have also found that there are many more different kinds of proteins in the human cells that there are different genes in the genome. How can this be explained?
The human genome project was an international effort to completely map the all of the genes of humans. The first information on the human genome generated from this endeavor was published in 2000 and the full sequence was published in 2003. Since then, estimates of the rumber of genes in the human genome have steadily declined, and it is now though that there are about 20,500 genes in the human genome, but the exact number is yet to be determined. Since we have known the sequence of the human genome for almost two decades, why are scientists still not sure of the total number of genes contained within the human genome? In other words, why is it taking so long to determine the number of genes humans have?
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