Evolutionary Analysis (5th Edition)
5th Edition
ISBN: 9780321616678
Author: Jon C. Herron, Scott Freeman
Publisher: PEARSON
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Chapter 1, Problem 4Q
Given the risk of evolution of resistance, why do you think the two patients shown in Figure 1.11 were not given high doses of AZT immediately, rather than starting them with low doses?
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Three of the many recessive mutations in Drosophila melanogaster that affect body color, wing shape, or bristle morphology are black (b) body versus grey in wild type, dumpy (dp), obliquely truncated wings versus long wings in the male, and hooked (hk) bristles versus not hooked in the wild type. From a cross of a dumpy female with a black and hooked male, all of the F1 were wild type for all three of the characters. The testcross of an F1 female with a dumpy, black, hooked male gave the following results:
Trait
Number of individuals
Wild type
169
Black
19
Black, hooked
301
Dumpy, hooked
21
Hooked, dumpy, black
172
Dumpy, black
6
Dumpy
305
Hooked
8
Determine the order of the genes and the mapping distance between genes.
Determine the coefficient of confidence for the portion of the chromosome involved in the cross. How much interference takes place in the cross?
Chapter 1 Solutions
Evolutionary Analysis (5th Edition)
Ch. 1 - Prob. 1QCh. 1 - Prob. 2QCh. 1 - Prob. 3QCh. 1 - Given the risk of evolution of resistance, why do...Ch. 1 - Prob. 5QCh. 1 - Prob. 6QCh. 1 - In a monograph published in 1883, Alexander Graham...Ch. 1 - Design a study to test our prediction that human...Ch. 1 - Prob. 9QCh. 1 - Suppose that HIV were the ancestor of the SIVs,...
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