You have synthesized an oligopeptide containing an RGD motif surrounded by other amino acids. What is the effect of this peptide when added to a fibroblast cell culture grown on a layer of fibronectin adsorbed to the tissue culture dish? Why does this happen?

Q: Based on what you know about the structure of GPCRs, they must have: a)One internal start transfer…

A: Proteins destined for secretion outside the cell or lumen of an organelle are first targeted to the…

Q: What is the mechanism of the Contactin- BIG-2

A: Contactins are a subfamily of immunoglobulin molecules that are only found in the nerve system and…

Q: Measure the uptake of leucine by epithetial cells of the mouse intestine. rements of the rate of…

A: Leucune Transport is example of facilitated transport which is the passive transport of the amino…

Q: What structural features make glycans good cell-surface markers? What are the main challenges to…

A: Step 1 Glycans are sugar molecules that are often attached to proteins and lipids on the surface of…

Q: Chlamydia are pathogenic bacteria that must be grown within a eukaryotic host cell. They rely on the…

A: Introduction:- Chlamyadiaceae are obligate intracellular bacterial pathogens that strictly depend on…

Q: Usually, bacteria only make tryptophan when tryptophan is absent or available in low concentration.…

A: Normally, bacteria regulate the synthesis of tryptophan through the trp operon. When tryptophan…

Q: Palivizumab is a humanized monoclonal anitbody for the prohylaxis of resporatory diseases caused by…

A: Palivizumab is a humanized monoclonal anitbody developed to help protect against respiratory…

Q: I need to make an antibody for the extracellular portion of the Notch receptor. I have made S35…

A: Hybridoma technology is used to produce a large number of monoclonal antibodies. Monoclonal…

Q: Penicillin is an irreversible inhibitor of the transpeptidases, enzymes that cross-link components…

A: Antibiotics is formed of :-  Anti + Biotics  Anti means against while biotics means living microbes…

Q: Receptor tyrosine kinases such as the epidermal growth factor (EGF) receptor can basically be broken…

A: Receptor tyrosine kinases (RTKs) are a group of membrane-bound receptors that act as signal…

Q: A Cys residue is required for the transport function of a bacterial lactose transporter that is…

A: N-Ethylmaleimide (NEM) has been much used for the chemical modification of proteins, and  it is…

Q: Actinomycin D inhibits DNA-dependent RNA synthesis. This antibiotic is added to a bacterial culture…

A: Antibiotics are isolated from microorganisms (bacteria). They use antibiotics to inhibits the growth…

Q: The codon change (Gly-12 to Val-12) in human rasH that convertsit to oncogenic rasH has been…

A: The codons are the triplet sequences of the nucleotides like DNA (deoxyribonucleic acid) and RNA…

Q: Based on the UCP1 protein structure and the figure above, what are the likely chemical properties of…

A: UCP 1 protein: The UCP1 (uncoupling protein 1) protein is a mitochondrial protein found in brown…

Q: Can you explain the experimental procedure from this article? Please explain as if your having…

A: In this work, the role of inositol 1,4,5-trisphosphate receptor (InsP3R) and Na, K-ATPase in the…

Q: Describe the molecule shown in the image. Evaluation at Atomic Resolution of the Role of Strain in…

A: T4 lysozymes helps to release the phage particles synthesized inside the host cell via hydrolyzing…

Q: Cholera is an acute, diarrheal disease caused by infection of the intestine with the gram-negative,…

A: Proteins are high molecular weight biomolecules made up of amino acid residues linked via peptide…

Q: A cytokine/growth factor that induces inflammation and promotes cell death. a) Cdk1 Ob) TNF O c)…

A: Tumor necrosis factor (TNF) is a cytokine that plays a critical role in the inflammatory response.…

Q: What amino acid residues are phosphorylated on the intracellular domain of a VEGFR? Glutamic Acid…

A: VEGFR: VEGF receptors are vascular endothelial growth factor receptors (VEGF). VEGFR is divided into…

Q: First, you apply a signaling ligand known to activate this Gs protein and track yellow fluorescence.…

A: G protein coupled receptors are the cell surface receptors and transmit signals to their…

Q: cientists used a Rat6-Raf transformed cell line for the anchorage-independent growth control…

A: The Rat6-Raf cell line is a transformed cell line that contains an activated form of Raf. In this…

Q: I have this strain of e coli.  Is P+ o+ Z+ Y+ / I- P+ oC Z- Y+ Will beta-galactosidase and…

A: Lac operon constitutes a set of structural genes regulated by a common promoter in bacteria.

Q: Yeast cells are eukaryotes, and they require a functional secretory pathway to grow and to maintain…

A: Yeast are single-celled microorganisms. These are classified, along with molds and mushrooms, as…

Q: For any antibiotic compounds that don’t appear to inhibit translation of proteins from the ribosome,…

A: Antibiotics that target translation interfere with the ribosome's assembly or processing.

Q: Describe how one might determine which protein in E. coli are repressed when a culture is shifted…

A: The Escherichia coli is a facultatively anaerobic, rod-shaped, gram-negative, coliform bacterium.…

Q: What mechanistic features are shared by (a) the formation of multivesicular endosomes by budding…

A: Mature endosomes are also known as multivesicular bodies (MVBs) or multivesicular endosomes. Initial…

Q: Describe how one might determine which proteins in E.coli are repressed when a culture is shifted…

A: Introduction  Gene expression is the process through which information from a gene is used to make a…

Q: What is the major difference between bacterial ribosomes and eukaryotic ribosomes that makes it…

A: Prokaryotes are the organisms that possess primitive cellular organization such as bacteria. They do…

Q: What effect does binding of the IRF protein to the IRE in the mRNA encoding ferritin have on the…

A: Iron regulatory proteins(IRP) are previously known as IRF or IRE-BP. They plays a major role in iron…

Q: Genetic testing of a 29-month-old boy shows a mutation in the Phe residue at position 508 in the…

A: Cystic fibrosis is a fatal genetic disease which is caused due to defect in CF transmembrane…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.