How does the loss of the Adenomatous polyposis coli (APC) protein lead to the deregulation of Beta-catenin functions in FAP patients?

Q: What type of DNA changes are revealed from p.Gln39X mutation. Is it pathogenic?

A: Introduction: Mutations are the change in the nucleotide sequence of DNA. It may occur in somatic…

Q: Question 1 Bacteria Bacterial Morphology, prepared slide A. B. C.

A: Microbiology is the branch of biology that deals with study of organisms that are too small to be…

Q: I need to make an antibody for the extracellular portion of the Notch receptor. I have made S35…

A: Hybridoma technology is used to produce a large number of monoclonal antibodies. Monoclonal…

Q: Pompe disease is due to a deficiency in lysosomal α-1,4-glucosidase, also called acid maltase.…

A: Pompe disease was named after Johann Pompe who identified the disease in 1932. It is a lysosomal…

Q: The ras protein is a mutated G protein that lacks GTPase activity. How does the absence of this…

A: G protein is a membrane protein whose target is a membrane associated adenylyl cyclase enzyme. when…

Q: How closely related are the amino acid sequences between SARS-Cov-2 and SARS-CoV? what does this…

A: SARS-CoV-2 and SARS-CoV are both coronaviruses that belong to the same family of viruses. They are…

Q: how UTI's could be prevented ?

A: UTI is urinary tract infection. It is an infection in the urinary system like kidneys, ureters,…

Q: Tay-Sachs disease is result from a)malfunction of cerebroside metabolism b)the accumulation of GM2…

A: Tay Sachs disease is a recessively inherited genetic disease. It is characterised by the destruction…

Q: Explain what is c-myc translocation and why it results in overexpression of c-myc. What is the role…

A: Epstein-Barr virus or EBV is one of the most common viruses found in the human body. They pass from…

Q: Which of the following epidermal growth factor (EGF) receptors cannot bind ligands but will form…

A: Epidermal growth factor (EGF) is a protein that plays a key role in the regulation of cell growth,…

Q: Cholera is an acute, diarrheal disease caused by infection of the intestine with the gram-negative,…

A: Proteins are high molecular weight biomolecules made up of amino acid residues linked via peptide…

Q: Which statement among A-D is false regarding bacterial toxins? A) O Hemolysins are cell membrane…

A: Toxins refer to poisonous substances that include a class of small molecules and proteins, which are…

Q: What would happen if the retinoblastoma protein wasn't able to bind to the E2F transcription factor?

A: The retinoblastoma protein (pRb) is a tumor suppressor protein that helps to prevent excessive cell…

Q: Mutations in the IL2RG gene cause approximately 30 percent of severe combined immunodeficiency…

A: Since we answer only three subparts of a question at a time, therefore we are answering the first…

Q: Which form of Retinoblastoma typically results in unilateral disease and exhibits 2-hit mutational…

A: Retinoblastoma is a cancer that affects the eyes. It is specifically a cancer of retinal layer of…

Q: Fetal hemoglobin comprises of αγ sub-units. It has been found that the γ-chain contains serine at…

A: Introduction:- Fetal hemoglobin (HbF) is a prominent type of hemoglobin that is present in the fetus…

Q: Identify two ways in which IL-1β is regulated so as to minimize its destructive potential in the…

A: A prime factor involved in host immune response to infection or injury is Interleukin-1β (IL-1β), a…

Q: Which of the following dephosphorylates PI 3,4,5-trisphosphate, thereby blocking the activation of…

A: The survival and growth is promoted by the PI3K-Akt signaling pathway. Protein Kinase B and…

Q: Why is phospholipase c is the target on this western blot explain in detail

A: Phospholipase C (PLC) is an enzyme that cleaves the phospholipids just before the attachment of…

Q: The synaptosome-associated receptors referred to as t-SNARES can be found, as transmembrane…

A: SNARE proteins or SNAP (synaptosome associated proteins) receptors are the proteins that are…

Q: How do loss of function mutations associated with Artemis (protein) cause their resulting…

A: Introduction: -Artemis is a protein that in humans is encoded by the DCLRE1c gene.  Function: -…

Nitrogen metabolism

Nitrogen metabolism is the synthesis, utilization or uptake, breakdown, and excretion of nitrogenous compounds in the body. The nitrogen metabolism encompasses nitrogen fixation, biosynthesis, and the breakdown of amino acids, purines, and pyrimidine. Since nitrogen-containing compounds are required for various life processes, nitrogen is an important element of life.