You are treating a patient with breast cancer and assay indicates that their plasma PDGF level 6 fmoles/ 100 uL.Based on this info, in which stages has this patient's cancer progressed? Explain what process this patient's tumor has likely undergone and which cell types you would expect to now be associated with this tumor.

Human Anatomy & Physiology (11th Edition)
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Plasma PDGF levels can be a diagnostic marker for severity and progression of breast cancer. The assay data below shows the plasma levels of PDGF in normal individuals, Stage II and Stage IV (More severe). You are treating a patient with breast cancer and assay indicates that their plasma PDGF level 6 fmoles/ 100 uL.Based on this info, in which stages has this patient's cancer progressed? Explain what process this patient's tumor has likely undergone and which cell types you would expect to now be associated with this tumor.

 

The image is a scatter plot that shows the concentration of a specific substance measured in fmol/100μl of plasma. The x-axis represents three groups: Controls, Stage II Breast Cancer, and Stage IV Breast Cancer. The numbers in parentheses under each group label indicate the sample sizes: 8 for Controls, 15 for Stage II, and 23 for Stage IV.

The y-axis displays the concentration levels ranging from 0 to 8 fmol/100μl plasma. Two horizontal dashed lines appear slightly above 2.0 and 3.0 fmol/100μl, indicating possible reference levels or thresholds.

Observations:

- Controls: Data points are mostly clustered around the lower values, with two measurements near the 2.0 fmol/100μl line.
  
- Stage II Breast Cancer: The data points are distributed around the 3.0 fmol/100μl dashed line, suggesting a slight increase compared to the control group, with a few measurements above and below this level.

- Stage IV Breast Cancer: A noticeable shift in distribution, with many data points exceeding 3.0 fmol/100μl, and some concentrations reaching up to near 8.0 fmol/100μl, indicating higher levels in this group.

This scatter plot suggests varying degrees of concentration across the different groups, with Stage IV Breast Cancer patients showing the highest levels.
Transcribed Image Text:The image is a scatter plot that shows the concentration of a specific substance measured in fmol/100μl of plasma. The x-axis represents three groups: Controls, Stage II Breast Cancer, and Stage IV Breast Cancer. The numbers in parentheses under each group label indicate the sample sizes: 8 for Controls, 15 for Stage II, and 23 for Stage IV. The y-axis displays the concentration levels ranging from 0 to 8 fmol/100μl plasma. Two horizontal dashed lines appear slightly above 2.0 and 3.0 fmol/100μl, indicating possible reference levels or thresholds. Observations: - Controls: Data points are mostly clustered around the lower values, with two measurements near the 2.0 fmol/100μl line. - Stage II Breast Cancer: The data points are distributed around the 3.0 fmol/100μl dashed line, suggesting a slight increase compared to the control group, with a few measurements above and below this level. - Stage IV Breast Cancer: A noticeable shift in distribution, with many data points exceeding 3.0 fmol/100μl, and some concentrations reaching up to near 8.0 fmol/100μl, indicating higher levels in this group. This scatter plot suggests varying degrees of concentration across the different groups, with Stage IV Breast Cancer patients showing the highest levels.
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