With only one exception, the most commonly used STR loci are spread across the human genome, each on a separate chromosome. a. Why is it important to analyze STRs that are all on their own chromosomes? b. What is the exception to this? (i.e., which two loci are on the same human chromosome and which chromosome are they on?)

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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With only one exception, the most commonly used STR loci are spread across the human genome,
each on a separate chromosome.
a. Why is it important to analyze STRs that are all on their own chromosomes?
b. What is the exception to this? (i.e., which two loci are on the same human chromosome
and which chromosome are they on?)
c. Using the UCSC Genome browser, look up the two loci that you answered in 2.b. one at
a time. Include a rough hand-drawing or screenshot of the ideogram (pictograph,
example below) of the chromosome and mark the approximate location of each locus.
Example:
d. Using your answer in 2.c. and your knowledge of the frequency of crossover events on
human chromosomes (see chapters 5 and 6), in your opinion is the fact that these two
loci are on the same chromosome a problem for forensic genetic analysis? Explain your
answer

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