Why is it that Rh incompatibility can be a serious problem when anRh-negative mother is carrying an Rh-positive fetus, but ABOincompatibility between mother and fetus is usually no problem?That is, a type A mother can usually safely carry a type B fetus.(Hint: The antibodies produced by an Rh-negative mother againstthe Rh antigen are usually IgG, whereas the antibodies producedagainst the A or B antigens are IgM.) Because the Rh antigenobviously serves no vital function (most humans lack it), why do youthink it hasn’t been completely eliminated during human evolution?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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 Why is it that Rh incompatibility can be a serious problem when an
Rh-negative mother is carrying an Rh-positive fetus, but ABO
incompatibility between mother and fetus is usually no problem?
That is, a type A mother can usually safely carry a type B fetus.
(Hint: The antibodies produced by an Rh-negative mother against
the Rh antigen are usually IgG, whereas the antibodies produced
against the A or B antigens are IgM.) Because the Rh antigen
obviously serves no vital function (most humans lack it), why do you
think it hasn’t been completely eliminated during human evolution?

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