Which of the following statements regarding Nucleotide Excision Repair (NER) and Base Excision Repair (BER) is true?   Only NER involves the action of DNA ligase to seal nicks in the DNA backbone. Both NER and BER involve DNA strand cleavage by an endonuclease.   Both NER and BER can be activated by exposure to visible light. Only BER requires DNA polymerase.   Both NER and BER involve the creation of an apyrimidinic (AP) site.

Q: Which of the following enzymes can recognize and remove a damaged DNA base to leave an apurinic or…

A: There are different types of repair system in body which repairs damage DNA.

Q: Please explain one type of “DNA repair” mechanism (what is it, when is it used, how does it work).

A: The process by which a cell detects and repairs damage to the DNA molecules that encode its genome…

Q: Which of the following DNA repair mechanisms relies on homologous DNA recombination for the repair…

A: DNA repair mechanisms relies on homologous DNA recombination for the repair processes are :  SoS…

Q: True or false: After chromosomal replication, Type I topoisomerase is used to coil up the…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: A pyrimidine dimer which is a bulky lesion has mutated an E. coli cell's DNA. Describe both the…

A: The DNA damage can be repaired by several mechanisms that includes direct repair, excision repair,…

Q: Name of a few enzymes involved in DNA replication other than DSNA polymerase and ligase.name the key…

A: Each cell follows central dogma to undergo division and growth. The central dogma has three main…

Q: When single damaged bases are recognized and removed, it is referred to as base excision repair.…

A: DNA (deoxyribonucleic acid) is a molecule that carries the genetic information of an organism. It…

Q: Which of the following DNA repair mechanisms involves the 3’ to 5’ exonuclease function of DNA…

A: Given:   DNA repair mechanisms involves the 3’ to 5’ exonuclease function of DNA polymerase.

Q: DNA ligases cannot join the sticky ends of two DNA fragments. True False

A: The DNA ligases are used in the process of cloning in which pieces of DNA having matching ends are…

Q: In denatured DNA, DNA double helix is disrupted, which causes the exposure of the bases and thus…

A: The correct option is the C option: In denatured DNA, DNA double helix is disrupted, which causes…

Q: Among the different types of DNA repair, one has the unique ability to detect which strand is the…

A: A DNA sequence can be changed in the process of DNA replication because of the mistake of DNA…

Q: The general excision repair pathway for DNA repair has the following order   A. endonuclease cuts…

A: When there is an exposure of any mutagens either UV radiation or chemicals, there is the occurrence…

Q: Provide a detailed description and hand drawn figure of each of the following. (1) Mismatch…

A: Although the genetic variation is important for evolution, the survival of the individual demands…

Q: Each peak in a chromatogram corresponds to: A fluorescent ddNTP which has been released from the…

A: Ans-.  A fluorescent ddNTP which has been incorporated into the DNA fragment resulting in the…

Q: DNA polymerases have exonuclease activity that hydrolyzes DNA in the 3′ to 5′ direction. When an…

A: DNA POLYMERASE: DNA polymerase is an enzyme that plays a key role in the replication of DNA, the…

Q: Which of the following is true of DNA repair?

A: DNA repair is the process by which a cell identifies any damage in the DNA and rectifies it. It is…

Q: can someone explain the picture in simple terms? how does the parp inhibitor work

A: PARP or Poly ADP Ribose Polymerase is a proteinaceous enzyme responsible for repairing damaged DNA…

Q: Deamination of adenine results in the formation of hypoxanthine. Hypoxanthine selectively base pairs…

A: The question is asking about the potential outcome of a specific type of mutation in DNA,…

Q: A mutation occurs that changes a codon from UCC to UCA. It turns out that this codon is for an amino…

A: Based on the nature of change that occurs in a codon due to a point mutation (mutation at a single…

Q: Match the DNA repair mechanism to the type of repair it fixes.   Base excision repair DNA polymerase…

A:

Q: Which of the following enzymes can recognize and remove a damaged DNA base to leave an apurinic or…

A: Genetic variation is very important for evolution, but genetic stability is crucial for survival…

Q: Which of the following is/are true of DNA general recombination? The process involves invasion of a…

A: DNA recombination in general is a natural process that occurs in a wide range of organisms,…

Q: Explain endogenous and exogenous sources and how this relates to dna damage repair and recognition.…

A: Approach to solving the question: Detailed explanation: Examples: Key references:(1)…

Q: The sequence of the start of the c-Myc gene is as follows (first picture): Use this information to…

A: Transcription takes place on the strand called as template strand it has a polarity of 3' - 5', thus…

Q: Which of the following enzymes is needed to produce mRNA?     ligase     helicase     DNA…

A: Question -  Which of the following enzymes is needed to produce mRNA? A.)   ligase B.)…

Q: Some antibiotic drugs fight infection by interfering with DNA replication, transcription, or…

A: The central dogma of molecular biology explains how the instructions within the DNA of an organism…

Q: DNA glycosylase inhibitors are used to study which DNA repair mechanism?

A: DNA glycosylase inhibitors are used to which DNA repair mechanism?

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.