can someone explain the picture in simple terms? how does the parp inhibitor work

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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can someone explain the picture in simple terms? how does the parp inhibitor work?

PARP-mediated SSB Repair
Intact DNA
MX
Intact DNA
1000
DNA Damage
PARP
SSB DNA
MA
DNA Damage
BRCA1/2-mediated
DSB Repair
Replication
Olaparib
49
SSB DNA
MA
Replication
BRCA1/2-mutation
DSB DNA
3:
DSB DNA
xx
Error-prone
DNA repair
Error-prone
DNA repair
A
Erroneous
DNA
1000
B
Erroneous
DNA
1000
Unrepairable DNA Damage
Cell Death
Transcribed Image Text:PARP-mediated SSB Repair Intact DNA MX Intact DNA 1000 DNA Damage PARP SSB DNA MA DNA Damage BRCA1/2-mediated DSB Repair Replication Olaparib 49 SSB DNA MA Replication BRCA1/2-mutation DSB DNA 3: DSB DNA xx Error-prone DNA repair Error-prone DNA repair A Erroneous DNA 1000 B Erroneous DNA 1000 Unrepairable DNA Damage Cell Death
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