photo-active platinum-based anticancer drugs
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Which statement(s) is(are) true about photo-active platinum-based anticancer drugs?
A. The drug is not active until it is avtivated using a specific wavelength of light.
B. Upon photoactivation, the complex udergoes a reduction and makes a Pt(II) complex.
C. Pt(IV) complex can bind to DNA.
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by Bartleby Expert- When Zidovudine (3'-azidothymidine or AZT) is added directly to an assay measuring the rate of DNA synthesis catalyzed by the AIDS virus reversed transcriptase, AZT is shown to be without significant inhibitory activity. Explain how AZT is metabolized in virus infected cells to convert the nucleoside into a potent and effective reversed transcriptase inhibitor.Resistance to many penicillins is the result of cell wall mutations in a variety of bacteria. True or false?The transpeptidase activity of penicillin binding proteins (PBP) promotes: please explain and choice the roght answer a.the addition of N-acetyl glucosamine to N-acetyl muramic acid b.,peptide crosslink formation between murein subunits c.the addition of murein precursors to a growing polymer d.beta lactamase binding to PBP
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