Which of the following statements are TRUE? Multiple answers are accepted for this question a .Two molecules of CO2 are produced each time a molecule of Acetyl-CoA is oxidized. b. During the first turn of the TCA Cycle the carbon atoms of Acetyl-CoA become CO2. c. The number of molecules of ATP that can be produced in the Citric Acid Cycle by substrate level phosphorylation of ADP from two molecules of Acetyl-CoA is 30. d. Fumarate contains a trans double bond. The cis isomer of Fumarate is Maleate which cannot serve as carbon source for a cell. e. Lack of O2 would decrease the rate of the Citric Acid Cycle in red blood cells. f. If a potent inhibitor of Succinyl-CoA Synthetaseis is applied to liver cells both energy production and synthesis of carbohydrate would be affected. g. The overall chemical changes that occur during one complete turn of the Citric Acid Cycle is the complete oxidation of one molecule of Acetyl-CoA plus the production of two molecules of CO2 plus the reduction of two molecules of NAD+ and one of FAD plus the phosphorylation of one molecule of GDP/ADP. h. In the Citric Acid Cycle only 1 ATP equivalent is directly produced but the reoxidation of NADH and FADH2 yields an additional 10 molecules of ATP by electron transport and oxidative phosphorylation. i. If the concentration of Acetyl-CoA is high (perhaps from degradation of fat) this will also tend to inhibition of Pyruvate Dehydrogenase thus conserving the levels of Pyruvate through inhibition of its conversion to Acetyl-CoA. Acetyl-CoA causes the activation of Pyruvate Carboxylase which causes an increase in Oxaloacetate. A lack of Oxaloacetate precludes the conversion of Acetyl-CoA to Citrate resulting in a high level of Acetyl-CoA
Which of the following statements are TRUE?
Multiple answers are accepted for this question
a .Two molecules of CO2 are produced each time a molecule of Acetyl-CoA is oxidized.
b. During the first turn of the TCA Cycle the carbon atoms of Acetyl-CoA become CO2.
c. The number of molecules of ATP that can be produced in the Citric Acid Cycle by substrate level phosphorylation of ADP from two molecules of Acetyl-CoA is 30.
d. Fumarate contains a trans double bond. The cis isomer of Fumarate is Maleate which cannot serve as carbon source for a cell.
e. Lack of O2 would decrease the rate of the Citric Acid Cycle in red blood cells.
f. If a potent inhibitor of Succinyl-CoA Synthetaseis is applied to liver cells both energy production and synthesis of carbohydrate would be affected.
g. The overall chemical changes that occur during one complete turn of the Citric Acid Cycle is the complete oxidation of one molecule of Acetyl-CoA plus the production of two molecules of CO2 plus the reduction of two molecules of NAD+ and one of FAD plus the phosphorylation of one molecule of GDP/ADP.
h. In the Citric Acid Cycle only 1 ATP equivalent is directly produced but the reoxidation of NADH and FADH2 yields an additional 10 molecules of ATP by electron transport and oxidative phosphorylation.
i. If the concentration of Acetyl-CoA is high (perhaps from degradation of fat) this will also tend to inhibition of Pyruvate Dehydrogenase thus conserving the levels of Pyruvate through inhibition of its conversion to Acetyl-CoA. Acetyl-CoA causes the activation of Pyruvate Carboxylase which causes an increase in Oxaloacetate. A lack of Oxaloacetate precludes the conversion of Acetyl-CoA to Citrate resulting in a high level of Acetyl-CoA.
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
