Which of the following is FALSE about Griffith's experiment with Streptococcus pneumonia? O the mouse did not survive when injected with a mixture of live Rough S. pneumonia and heat-killed Smooth S. pneumonia the heat-killed Smooth S. pneumonia was not lethal to the mouse. O the mouse survived injection of the live Rough S. pneumonia because of the polysaccharide coat surrounding the bacteria none of the answers are false, all are true statements O his results showed that there was a transforming agent in the heat killed S cells

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### Understanding Griffith's Experiment with Streptococcus Pneumonia

#### Question:
Which of the following is FALSE about Griffith’s experiment with Streptococcus pneumonia?

#### Options:
1. **The mouse did not survive when injected with a mixture of live Rough S. pneumonia and heat-killed Smooth S. pneumonia.**
2. **The heat-killed Smooth S. pneumonia was not lethal to the mouse.**
3. **The mouse survived the injection of the live Rough S. pneumonia because of the polysaccharide coat surrounding the bacteria.**
4. **None of the answers are false, all are true statements.**
5. **His results showed that there was a transforming agent in the heat-killed S cells.**

In this question, you are asked to identify the statement that is incorrect based on the famous experiment conducted by Frederick Griffith in 1928. Griffith's experiment demonstrated the phenomenon of bacterial transformation, where hereditary material from dead bacteria could be transferred to live bacteria, causing a change in phenotype. 

#### Detailed Explanation:
- **Statement 1**: This statement is true. Griffith's experiment showed that mice did not survive when injected with a mixture of live Rough (non-virulent) S. pneumonia and heat-killed Smooth (virulent) S. pneumonia.
  
- **Statement 2**: This is also true. Heat-killed Smooth S. pneumonia on its own was not lethal to the mouse, as the bacteria were no longer alive.
  
- **Statement 3**: This statement is FALSE. The mouse did not survive the injection of the live Rough S. pneumonia when it was combined with heat-killed Smooth S. pneumonia because the transformation occurred. The live Rough bacteria acquired the polysaccharide coat from the dead Smooth bacteria, making them virulent.
  
- **Statement 4**: This is incorrect because there is a false statement in the list (Statement 3).
  
- **Statement 5**: This statement is true. Griffith’s results indicated that there was some form of transforming agent that allowed the Rough bacteria to acquire virulence from the heat-killed Smooth bacteria, which later was identified as DNA.

Grasping these principles helps build a foundation in understanding genetic transformation and the molecular basis of heredity.

### Key Takeaway:
In Griffith’s experiment, the key discovery was the identification of a "transforming principle," which was later found to be DNA, showcasing the ability of genetic material to be transferred between cells
Transcribed Image Text:### Understanding Griffith's Experiment with Streptococcus Pneumonia #### Question: Which of the following is FALSE about Griffith’s experiment with Streptococcus pneumonia? #### Options: 1. **The mouse did not survive when injected with a mixture of live Rough S. pneumonia and heat-killed Smooth S. pneumonia.** 2. **The heat-killed Smooth S. pneumonia was not lethal to the mouse.** 3. **The mouse survived the injection of the live Rough S. pneumonia because of the polysaccharide coat surrounding the bacteria.** 4. **None of the answers are false, all are true statements.** 5. **His results showed that there was a transforming agent in the heat-killed S cells.** In this question, you are asked to identify the statement that is incorrect based on the famous experiment conducted by Frederick Griffith in 1928. Griffith's experiment demonstrated the phenomenon of bacterial transformation, where hereditary material from dead bacteria could be transferred to live bacteria, causing a change in phenotype. #### Detailed Explanation: - **Statement 1**: This statement is true. Griffith's experiment showed that mice did not survive when injected with a mixture of live Rough (non-virulent) S. pneumonia and heat-killed Smooth (virulent) S. pneumonia. - **Statement 2**: This is also true. Heat-killed Smooth S. pneumonia on its own was not lethal to the mouse, as the bacteria were no longer alive. - **Statement 3**: This statement is FALSE. The mouse did not survive the injection of the live Rough S. pneumonia when it was combined with heat-killed Smooth S. pneumonia because the transformation occurred. The live Rough bacteria acquired the polysaccharide coat from the dead Smooth bacteria, making them virulent. - **Statement 4**: This is incorrect because there is a false statement in the list (Statement 3). - **Statement 5**: This statement is true. Griffith’s results indicated that there was some form of transforming agent that allowed the Rough bacteria to acquire virulence from the heat-killed Smooth bacteria, which later was identified as DNA. Grasping these principles helps build a foundation in understanding genetic transformation and the molecular basis of heredity. ### Key Takeaway: In Griffith’s experiment, the key discovery was the identification of a "transforming principle," which was later found to be DNA, showcasing the ability of genetic material to be transferred between cells
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