Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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
Transcribed Image Text:### CDK and Cyclin Targeted by p53 in DNA Damaged Conditions
**Question:** Which CDK and cyclin does p53 ultimately target in DNA damaged conditions?
- ☐ CDK1/cyclin E
- ☐ CDK2/cyclin E
- ☑ CDK1/cyclin B
- ☐ CDK2/cyclin B
In conditions where DNA is damaged, the p53 protein plays a crucial role in cell cycle regulation. Specifically, p53 targets CDK1 associated with cyclin B. This interaction is essential in halting the cell cycle to prevent propagation of the damage, thus ensuring genomic stability.
Note: The correct answer is selected in the provided multiple-choice options: **CDK1/cyclin B**.
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