Answered: What's the simple rule to predict…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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What's the simple rule to predict ligand binding sites for Rossmann Fold

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Proteins are polypeptides consisting of unbranched polymers constructed from 22 standard α-amino acids. They have four levels of structural organization and undergo folding to attain functional specificity. These distinct structural levels are known as primary, secondary, tertiary and quarternary structures of a protein. Certain combinations of secondary structures with a specific geometric arrangement are present in many proteins which are a combination of α-helix and β-pleated sheets. When an antiparallel β-strand folds back on itself in a pattern which resembles a common Greek pottery design, it is called the Greek key motif

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