What is the probability "Person X" who is African American has 14 repeats on one copy of chromosome 3, site D3S1358, and 18 repeats on the other copy? What is the probability "Person Y" who is Caucasian has 11 repeats on on both copies of chromosome 18, site D18S51?
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What is the probability "Person X" who is African American has 14 repeats on one copy of chromosome 3, site D3S1358, and 18 repeats on the other copy?
What is the probability "Person Y" who is Caucasian has 11 repeats on on both copies of chromosome 18, site D18S51?
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- Here is a depiction of the position of several genes on 2 chromosomes, with a dash "-" depicting the position of the centromere. Chromosome A has genes ABCD-EFGHIJ Chromosome B has genes 1234-56789. Please name the kind of rearrangement that would result in the following derivative chromosomes: 12D-EFGHIJ AB4-56789 O Unbalanced reciprocal translocation Unbalanced nonreciprocal translocation Balanced reciprocal translocation Balanced nonreciprocal translocationARVC5 is a disorder characterized by the replacement of healthy heart tissue with fatty fibrous tissue. Recent research has discovered the mutated gene that causes the disorder is on chromosome 3. People who have the mutation have a GCG triplet instead of the normal ACA triplet. The following is a section of a gene on chromosome 3: GGT GCG ACA ATT 1. Complete the following table. AA DNA sense strand DNA antisense strand GGT GCG ACA ATT mRNA tRNA 2. Indicate the change in the amino acid sequence resulting from the mutation in the gene described above., B I 123 ||| 14 E GO LG US X₂ x²Colchicine is a chemical mutagen that inhibits the spindle formation and prevents anaphase, which retains the cell’s single restitution nucleus (doubled chromosome number). Suppose that an onion (2n=16) is subjected to three consecutive rounds of colchicine treatment, what will be the resulting chromosome number of the treated onion?
- L, R, P and D are four genes located on the same chromosome in a diploid organism. Map distances between different pairs of genes were determined and the following results obtained. Based on these data, what is the order of the genes on the chromosome? D-R: 35 CM P-D: 5 CM L-R: 10 CM D-P: 30 CM D-L 25 CM P-R: 40 CM Note that only one orientation of the order is given as an answer choice. For example: ABCD has the same order as DCBA, but only ABCD would be listed as a possible answer. So be sure to check both orientations when comparing your gene order to the possible answer choices. D-L-P-R P-D-L-R P-R-D-L L-P-R-D R-L-D-P2 3 4 5 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 ху Which chromosome set has an extra What diagnosis would you give this patient?. Finish the notation for this patient's karyotype: What causes a dark band on the chromosome? What is a centromere?Why is chromosome 21 the smallest and not chromosome 22? considering that a karyogram is arranged from largest to smallest
- A phenotypically abnormal individual has a phenotypically normalfather with an inversion on one copy of chromosome 7 and a phenotypicallynormal mother without any changes in chromosomestructure. The orders of genes along the two copies of chromosome7 in the father are as follows: R T D M centromere P U X Z C (normal chromosome 7)R T D U P centromere M X Z C (inverted chromosome 7) The phenotypically abnormal offspring has a chromosome 7 withthe following order of genes: R T D M centromere P U D T R Using a sketch, explain how this chromosome was formed. In youranswer, explain where the crossover occurred (i.e., between whichtwo genes).Human adult hemoglobin is a tetramer containing two alpha (a) and two beta (b) polypeptide chains. The a gene cluster on chromosome 16 and the b gene cluster on chromosome 11 share amino acid similarities such that 61 of the amino acids of the a@globin polypeptide (141 amino acids long) are shared in identical sequence with the b@globin polypeptide (146 amino acids long). How might one explain the existence of two polypeptides with partially shared function and structure on two different chromosomes?describe a specific example of chromosome abnormality that leads to human cancers, such as leukemia, other than the Philadelphia chromosome that is derived from the translocation of chromosome 9 and 22
- Two phenotypically unaffected parents produce two children with familial Down syndrome. Regarding chromosome 14 and 21, what are the chromosomal composition of the parents?a) Are the genes linked? Please explain SPECIFICALLY how you can distinguish between linked and unlinked genes in this instance. b) If the two genes are linked, calculate the % recombination between ser and thr. Show the formula used, as well as all of your calculations. c) Draw a single map illustrating the arrangement of the two genes on the chromosome with respect to each other and to the centromere of the chromosome. Make sure to map ALL three distances.Below is a pedigree from one family (two parents and eight children). Four of the children (indicated by shaded shapes) are affected with a serious disease with an unknown genetic cause. a) For the disease, what pattern of inheritance (autosomal/sex-linked, recessive/dominant) is exhibited by this pedigree? b) Linkage analysis of the disease to a series of VNTR polymorphisms on human chromosome 5 is shown above. Is there evidence for linkage between the disorder and the VNTR? Briefly explain your answer.