What are the particular changes in the gene and protein sequences shown on the screen? Name the codons and amino acids.
What are the particular changes in the gene and protein sequences shown on the screen? Name the codons and amino acids.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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What are the particular changes in the gene and protein sequences shown on the screen? Name the codons and amino acids.

Transcribed Image Text:**Description of Genetic and Protein Sequences**
This image presents a comparison between mutant and wild-type nucleotide sequences and their corresponding protein translations.
---
**Mutant 104 Sequence:**
- **Nucleotide Sequence:**
- TAC TGC AAA TGG TCA CTT TTT TCA GCC TTA TAC GTT TTG
- **Amino Acid Sequence (Proteins):**
- Tyr - Cys - Lys - Trp - Ser - Leu - Phe - Ser - Ala - Leu - Tyr - Val - Leu
---
**Wild Type Sequence:**
- **Nucleotide Sequence:**
- TAC TGC ACA TGG TCA CTT TTT TCA GCC TTA TAC GTT TTG
- **Amino Acid Sequence (Proteins):**
- Tyr - Cys - Arg - Trp - Ser - Leu - Phe - Ser - Ala - Leu - Tyr - Val - Leu
---
**Highlighted Mutation:**
- **Mutation Site:** The third codon in the nucleotide sequence is where the mutation has occurred.
- **Mutant Codon:** AAA (Lysine)
- **Wild-Type Codon:** ACA (Arginine)
This indicates a single nucleotide change resulting in an amino acid substitution from Arginine (Arg) to Lysine (Lys) in the protein sequence. This substitution is boxed in red for clarity, highlighting the point mutation's effect on the protein chain.
---
This visualization helps illustrate how a genetic mutation can alter the resulting protein by changing a single amino acid, potentially impacting the protein's function or structure.
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