Original DNA sequence: mRNA transcript: amino acids: Mutated DNA sequence #3: mRNA transcript: (Circle any changes) amino acids: TAC AUG METH TAC ACC UGG TRP ACC H 11 JL TTG AAC ASN TTA GCG CGC ARG GCG ACG UGC CYS ACG 3 ACT ACT UGA STOP

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Transcribe and translate the mutated sequence #3.  Determine the consequence, if any, for each mutation.  You will need to use your codon charts in your ISN.  Practice with both charts.
 
 
 
Transcribe and translate the mutated sequence # 3. Determine the consequence, if any, for each mutation. You w
ISN. Practice with both charts.
Original DNA
sequence:
mRNA transcript:
amino acids:
Mutated DNA
sequence #3:
mRNA transcript:
(Circle any changes)
amino acids:
Type of
mutation
(Circle one.)
How did the
mutation affect
the amino acid
sequence
(protein)?
(Circle all that
apply)
Point
:: AAU :: AAC
TAC
AUG
METH
TAC
SILENT
(No
change)
ACC
:: ASN
UGG
TRP
ACC
Substitution
Missense
(1 amino
acid
changed)
:: CGC :: ARG
CYS
Mutated DNA sequence #3 is an example of
TTG
AAC
ASN
TTA
Nonsense
(Premature
stop)
signal
:: TRP
:: Stop
Substitution
Insertion
Deletion
GCG
CGC
ARG
GCG
Frameshift
No stop
signal
AUG
:: GLY
ACG
UGC
CYS
ACG
ACT
ACT
LEU
UGA
STOP
Insertion
1 amino acid
added/
deleted
:: UGA :: PRO
:: UGC
Deletion
All the amino aci
changed after t
point of mutatic
UGG
#H
Transcribed Image Text:Transcribe and translate the mutated sequence # 3. Determine the consequence, if any, for each mutation. You w ISN. Practice with both charts. Original DNA sequence: mRNA transcript: amino acids: Mutated DNA sequence #3: mRNA transcript: (Circle any changes) amino acids: Type of mutation (Circle one.) How did the mutation affect the amino acid sequence (protein)? (Circle all that apply) Point :: AAU :: AAC TAC AUG METH TAC SILENT (No change) ACC :: ASN UGG TRP ACC Substitution Missense (1 amino acid changed) :: CGC :: ARG CYS Mutated DNA sequence #3 is an example of TTG AAC ASN TTA Nonsense (Premature stop) signal :: TRP :: Stop Substitution Insertion Deletion GCG CGC ARG GCG Frameshift No stop signal AUG :: GLY ACG UGC CYS ACG ACT ACT LEU UGA STOP Insertion 1 amino acid added/ deleted :: UGA :: PRO :: UGC Deletion All the amino aci changed after t point of mutatic UGG #H
How did the mutation in sequence #3 affect the amino acid sequence (and as a result the protein)? Select ALL th
Silent (No change)
Missense (1 amino acid changed)
Nonsense (Premature STOP sign)
No stop signal
1 amino acid added/ deleted
All the amino acids changed after the mutation
Transcribed Image Text:How did the mutation in sequence #3 affect the amino acid sequence (and as a result the protein)? Select ALL th Silent (No change) Missense (1 amino acid changed) Nonsense (Premature STOP sign) No stop signal 1 amino acid added/ deleted All the amino acids changed after the mutation
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