The successful sequencing of the human genome The human genome holds an extraordinary amount of information about human development, medicine, and evolution. In 2000, the human genome was triumphantly released as a reference genome with approximately 8% missing information (gaps). In 2022- exactly 22 years later, technological advances enabled the gaps to be filled. This is a notable scientific milestone, leading to the resolution of critical aspects of human genetic diversity, including evolutionary comparisons to our ancestors. Discuss the sequencing technology used to resolve the human genome in 2005, its significant advantages and limitations? What was the technology used in 2022, and how significant are the gaps that have been resolved? What new insight will be gained from this new information- especially pertaining to understanding epigenetics?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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The successful sequencing of the human genome
The human genome holds an extraordinary amount of information about human
development, medicine, and evolution. In 2000, the human genome was triumphantly released
as a reference genome with approximately 8% missing information (gaps). In 2022- exactly 22
years later, technological advances enabled the gaps to be filled. This is a notable scientific
milestone, leading to the resolution of critical aspects of human genetic diversity, including
evolutionary comparisons to our ancestors. Discuss the sequencing technology used to resolve
the human genome in 2005, its significant advantages and limitations? What was the
technology used in 2022, and how significant are the gaps that have been resolved? What new
insight will be gained from this new information- especially pertaining to understanding
epigenetics?
Your work should be approx. 2 x A4 pages, written in Calibri font size 11, 1.5 spacing.
Only include academic peer-reviewed articles as references.
The Turn-it-in report for your essay should be less than 15% plagiarism.
RUBRIC
Theme
Marks
Introduction- background into the human
genome
Sequencing methods used in 2000- the
strength and limitations (This can include a
historical perspective of some of the
In
10
Transcribed Image Text:The successful sequencing of the human genome The human genome holds an extraordinary amount of information about human development, medicine, and evolution. In 2000, the human genome was triumphantly released as a reference genome with approximately 8% missing information (gaps). In 2022- exactly 22 years later, technological advances enabled the gaps to be filled. This is a notable scientific milestone, leading to the resolution of critical aspects of human genetic diversity, including evolutionary comparisons to our ancestors. Discuss the sequencing technology used to resolve the human genome in 2005, its significant advantages and limitations? What was the technology used in 2022, and how significant are the gaps that have been resolved? What new insight will be gained from this new information- especially pertaining to understanding epigenetics? Your work should be approx. 2 x A4 pages, written in Calibri font size 11, 1.5 spacing. Only include academic peer-reviewed articles as references. The Turn-it-in report for your essay should be less than 15% plagiarism. RUBRIC Theme Marks Introduction- background into the human genome Sequencing methods used in 2000- the strength and limitations (This can include a historical perspective of some of the In 10
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